the Risks of Menstrual Delay Medications and Headaches - Obstetrics and Gynecology

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Risks of Side Effects from Menstrual Regulation Medications


Hello Doctor, I recently had to travel abroad for work, so I went to the obstetrics and gynecology department to obtain medication to delay my menstruation.
My expected menstrual period is around June 12.
The doctor prescribed me nine days of Primolut N, which I started taking on June 5 at around 11 AM and continued until 2 PM.
So far, I have not experienced any discomfort.
However, after taking a pill today, I noticed that the leaflet mentions a potential side effect of thrombosis.
I also have a tendency to experience migraines (about once or twice a month), and when I have an episode, I take acetaminophen (the doctor also prescribed acetaminophen for me to use for headaches and menstrual cramps).
I would like to ask the doctor if it is safe to take this medication for a short period.
If I experience a headache during this time, can I still take pain relief medication? How long should I wait between doses?

Ms. Yu, 30~39 year old female. Ask Date: 2023/06/05

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, the chance of thrombosis is low, and it should be safe in the short term.
You can take acetaminophen for the headache.
If you still feel unwell, then you should see an internist.
Wishing you good health.

Reply Date: 2023/06/05

More Info


When considering the use of medications to delay menstruation, such as the one you mentioned (likely a form of hormonal therapy), it is crucial to understand both the benefits and potential risks associated with these drugs. You have expressed concern about the risk of thrombosis (blood clots) and its relationship to your history of migraines. Let's break this down.


Understanding the Medication
The medication you are taking, likely a progestin or combined hormonal contraceptive, can indeed have side effects, including an increased risk of thromboembolic events. This risk is particularly relevant for individuals with a history of migraines, especially if they experience aura, as this can further elevate the risk of stroke and other vascular complications.

Risks of Blood Clots
The risk of blood clots is generally higher in women who smoke, are over 35, have a history of migraines, or have other risk factors such as obesity or a family history of clotting disorders. If you have migraines that occur with aura, it is advisable to discuss this with your healthcare provider, as they may recommend alternative methods for delaying your period that carry a lower risk profile.


Headaches and Pain Management
Regarding your concern about headaches while taking this medication, it is common for hormonal changes to influence headache patterns. If you experience a headache while on this medication, you can typically use acetaminophen (Tylenol) as it is generally considered safe for short-term use. However, it is essential to follow the dosing instructions on the package or those provided by your physician.


Timing of Pain Relief
If you need to take acetaminophen for a headache, it is generally safe to take it as needed, but you should space doses according to the recommended guidelines (usually every 4 to 6 hours, not exceeding the maximum daily dose). If you find that you need to take pain relief frequently, or if your headaches worsen, it would be wise to consult your healthcare provider for further evaluation and management.


Short-Term Use Safety
Short-term use of hormonal medications to delay menstruation is usually considered safe for most women, especially if there are no contraindications. However, monitoring for any side effects, including headaches, mood changes, or any signs of thrombosis (such as swelling, pain in the legs, or sudden shortness of breath), is essential. If you notice any concerning symptoms, you should seek medical attention promptly.


Conclusion
In summary, while the short-term use of hormonal medications to delay menstruation can be safe, it is essential to consider your personal health history, especially regarding migraines and the risk of blood clots. Always communicate openly with your healthcare provider about your concerns and any side effects you experience. They can provide tailored advice and may suggest alternative options if necessary. Remember, your health and safety should always come first, and proactive communication with your doctor is key to managing any potential risks effectively.

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