How Long Should You Take Medication for Mild Prostate Enlargement? - Urology

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How long should medication be taken for mild benign prostatic hyperplasia?


I have mild benign prostatic hyperplasia causing urgency issues.
I have been prescribed Vesicare and Harnalidge, and I have been taking them for over a month.
Currently, I no longer have urgency problems, but I am experiencing dry mouth and mild constipation as side effects.
Can I stop taking the medication and resume it only when symptoms occur?

Andy, 60~69 year old female. Ask Date: 2023/06/08

Dr. Xu Wencang reply Urology


You can gradually taper off the medication and monitor the symptoms.
Follow up in the outpatient clinic for further evaluation.

Reply Date: 2023/06/08

More Info


When it comes to managing mild prostate enlargement, also known as benign prostatic hyperplasia (BPH), the duration of medication usage can vary significantly based on individual circumstances and the severity of symptoms. In your case, you have been prescribed Vesicare (solifenacin) and Harnalidge (tamsulosin) for over a month, and you are experiencing an improvement in your urinary urgency symptoms. However, you are also experiencing side effects such as dry mouth and mild constipation.

Firstly, it is essential to understand that medications for BPH, such as tamsulosin, work by relaxing the muscles in the prostate and bladder neck, which helps to improve urine flow and reduce symptoms. Vesicare, on the other hand, is an anticholinergic medication that helps reduce urinary urgency and frequency by relaxing the bladder muscles. While these medications can be effective in managing symptoms, they may also come with side effects, as you have experienced.

Regarding your question about whether you can stop taking the medications and resume them only when symptoms reappear, it is crucial to consult with your healthcare provider before making any changes to your medication regimen. In general, it is not uncommon for patients to consider discontinuing medications once their symptoms improve; however, there are several factors to consider:
1. Underlying Condition: BPH is a chronic condition that typically requires ongoing management. While you may feel better now, stopping medication could lead to a recurrence of symptoms. It is essential to monitor your condition closely.

2. Risk of Symptom Recurrence: If you stop taking the medication, there is a possibility that your symptoms may return. Some patients experience a return of symptoms within a few weeks to months after discontinuing treatment.

3. Potential for Increased Severity: In some cases, if symptoms return, they may be more severe than before. This could lead to complications such as urinary retention, which may require more aggressive treatment.

4. Side Effects Management: If the side effects you are experiencing are bothersome, discuss them with your doctor. They may be able to adjust your dosage, switch you to a different medication, or suggest strategies to manage these side effects without stopping treatment altogether.

5. Regular Follow-Up: Regular follow-up appointments with your healthcare provider are essential for monitoring your condition and adjusting treatment as necessary. If you are considering stopping medication, it is vital to have a discussion with your doctor about the best approach.

In summary, while it may be tempting to stop medication once symptoms improve, it is generally advisable to continue treatment as prescribed unless directed otherwise by your healthcare provider. They can provide personalized advice based on your specific situation, including the severity of your BPH, your response to treatment, and any side effects you may be experiencing. Always prioritize open communication with your healthcare team to ensure the best outcomes for your health.

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