Left chest tightness and discomfort, seeking advice on angina?
Hello, Director.
I would like to ask you to take some time to analyze the echocardiogram results for a 37-year-old female patient with no history of hypertension, diabetes, or hyperlipidemia, who does not smoke or drink alcohol, is slightly underweight, has a small amount of exercise habits, and does not stay up late.
She has a tendency to be anxious, leads a busy life, and has mild gastroesophageal reflux.
Laboratory results show:
- Hemoglobin (Hgb): 11.3 g/dL
- Hematocrit (Hct): 36.4%
- Mean Corpuscular Volume (MCV): 70.3 fL
- Mean Corpuscular Hemoglobin (MCH): 21.8 pg
- Mean Corpuscular Hemoglobin Concentration (MCHC): 31.0 g/dL
- Beta-thalassemia trait.
Electrocardiogram report indicates: Myocardial ischemia.
Diagnosis and examination purpose: Chest pain, dyspnea, and unspecified angina pectoris.
Echocardiographic findings:
- M-Mode, Two-Dimensional & Doppler Studies
- Right Ventricular Diameter (RVD): 1.3 cm (normal range: 0.7-2.3 cm)
- Mitral Valve Structure: Regurgitation velocity
- Left Ventricular Diastolic Dimension (LVDD): 4.4 cm (normal range: 3.5-5.5 cm)
- Ejection Fraction (EF): 57% (normal range: 50-70%)
- Left Ventricular Systolic Dimension (LVSD): 2.3 cm (normal range: 1.9-3.9 cm)
- Interventricular Septum (IVS): 0.7 cm (normal range: 0.5-1.2 cm)
- Aortic Root (Ao): 2.2 cm (normal range: 1.7-4.0 cm)
- Left Atrial Size (LA): 2.8 cm (normal range: 2.0-4.0 cm)
- Right Ventricular Systolic Pressure (RVSP): 31.1 mmHg indicating mild pulmonary hypertension.
Interpretation:
1.
Normal chamber size.
2.
Mitral valve prolapse (MVP) with trivial mitral regurgitation (MR).
3.
Tricuspid valve prolapse (TVP) with mild tricuspid regurgitation (TR).
4.
Mild pulmonary hypertension (RVSP: 31.1 mmHg).
5.
Normal thickness of IVS and left ventricular walls.
6.
Mild hypokinesia of IVS and left ventricular apex but preserved left ventricular systolic function (LVEF = 57%).
7.
Left ventricular diastolic dysfunction (pseudonormal mitral inflow velocity pattern).
At the end of May, the patient experienced occasional episodes of tightness and discomfort in the left chest, described as electric or stabbing sensations lasting about 3 seconds, with a minimum duration of 1 second.
The consulting physician mentioned myocardial ischemia and angina, prescribing Clopidogrel 30 mg TID, Aspirin 100 mg QD, and Concor 1.25 mg QD for one month.
I would like to ask:
1.
What is the current severity of the disease and what are the recommended follow-up treatment and examination directions?
2.
Can a patient with thalassemia trait take Aspirin long-term?
Thank you, Director.
Xiao Qi, 30~39 year old female. Ask Date: 2023/06/10
Dr. He Dongjin reply Cardiology
Hello, myocardial ischemia and angina? I haven't seen relevant evidence to assess the severity of the disease; perhaps an exercise electrocardiogram could be arranged? There shouldn't be significant issues with the echocardiogram.
If you're feeling uncomfortable, it might be due to anxiety causing autonomic nervous system problems.
Mediterranean anemia can be managed with long-term aspirin use, but is it necessary? Further evaluation may be needed.
Changhua Hospital cares about you.
Reply Date: 2023/06/10
More Info
Based on the information provided, it appears that you are experiencing chest discomfort and have been diagnosed with myocardial ischemia, which is a condition where the heart muscle does not receive enough blood flow, often due to narrowed arteries. Your echocardiogram results indicate mild hypokinesia of the interventricular septum (IVS) and left ventricular (LV) apex, mitral valve prolapse (MVP) with trivial mitral regurgitation (MR), mild tricuspid regurgitation (TR), and mild pulmonary hypertension. Additionally, you have a history of beta-thalassemia minor (Mediterranean anemia), which can affect your hemoglobin levels and overall blood health.
1. Severity of Current Condition and Recommended Follow-Up
Your current condition, characterized by myocardial ischemia, indicates that there is a potential risk for heart-related complications. The presence of mild hypokinesia suggests that there may be areas of the heart that are not contracting as effectively as they should, which can be a sign of underlying ischemia. The fact that you are experiencing episodes of chest tightness or discomfort, especially if they feel like electric shocks or stabbing pains, warrants careful monitoring and further evaluation.
Recommendations for Follow-Up:
- Cardiology Consultation: It is crucial to follow up with a cardiologist who can evaluate your symptoms in the context of your echocardiogram findings. They may recommend further diagnostic tests such as a stress test, coronary angiography, or advanced imaging techniques to assess the blood flow to your heart.
- Lifestyle Modifications: Given your anxiety and lifestyle factors, consider implementing stress management techniques such as mindfulness, yoga, or counseling. Regular, moderate exercise can also improve cardiovascular health, but it should be done under medical supervision, especially given your symptoms.
- Medication Management: You have been prescribed medications including a calcium channel blocker (Amlodipine), aspirin, and possibly a beta-blocker. It is important to adhere to these medications as they can help manage your symptoms and reduce the risk of further ischemic events. Regular follow-up appointments will help monitor the effectiveness and adjust dosages as necessary.
2. Long-Term Use of Aspirin with Mediterranean Anemia
Regarding your question about the long-term use of aspirin in the context of beta-thalassemia minor, aspirin is generally considered safe for individuals with this condition. However, it is important to monitor for any potential side effects, particularly gastrointestinal bleeding, as aspirin can increase the risk of bleeding. Regular blood tests to monitor your hemoglobin levels and overall blood health are advisable.
Considerations:
- Consult Your Hematologist: Since you have a history of Mediterranean anemia, it would be beneficial to discuss the use of aspirin with your hematologist. They can provide personalized advice based on your specific blood profile and any other underlying conditions.
- Monitor for Symptoms: Be vigilant for any signs of bleeding, such as unusual bruising, blood in stool, or prolonged bleeding from cuts. If you experience any of these symptoms, contact your healthcare provider immediately.
In conclusion, it is essential to take your symptoms seriously and maintain open communication with your healthcare providers. Regular follow-ups, appropriate lifestyle changes, and adherence to prescribed medications will be key in managing your condition effectively. If you have any further questions or concerns, do not hesitate to reach out to your healthcare team for guidance.
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