T15 Tumor Marker Test Results: Next Steps for Patients - Oncology

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T15 multi-tumor marker testing


Hello Doctor, I recently underwent a T15 tumor marker test, and the results showed two markers exceeding the normal range.
The first one is carbohydrate antigen CA72-4 with a result of 23.6, where the reference value is <5.3 U/ml.
The second one is tumor marker CA125 with a result of 41.5, where the reference value is <35.00 U/ml.
I would like to ask which specialty I should consult based on these test results.

mge, 20~29 year old female. Ask Date: 2003/12/22

Dr. Lin Zongzhe reply Oncology


Hello! The interpretation of serum tumor markers often requires correlation with medical history and other clinical examinations to be meaningful.
Many benign non-tumor diseases or even normal individuals may occasionally exhibit slight elevations in tumor markers.
You may inquire further with the clinic or hospital where your tests were conducted for additional consultation.
Sincerely, Dr.
Lin Tsung-Che, Department of Oncology, Taoyuan Hospital, Ministry of Health and Welfare.

Reply Date: 2003/12/22

More Info


When interpreting tumor marker test results, such as the T15 test you underwent, it is essential to understand what these markers indicate and the appropriate next steps for follow-up care. In your case, the results show elevated levels of two tumor markers: CA72-4 and CA125.
1. Understanding the Tumor Markers:
- CA72-4: This marker is often associated with gastric cancer but can also be elevated in other malignancies, including ovarian, colorectal, and pancreatic cancers. Your result of 23.6 U/ml is significantly above the normal reference range of <5.3 U/ml, which indicates a need for further evaluation.

- CA125: This marker is primarily associated with ovarian cancer but can also be elevated in other conditions, including endometriosis, pelvic inflammatory disease, and even benign tumors. Your result of 41.5 U/ml exceeds the normal reference value of <35.00 U/ml, suggesting a potential concern that warrants further investigation.

2. Next Steps:
- Consultation with a Specialist: Given the elevated levels of these tumor markers, the next step is to consult with a healthcare provider who specializes in oncology or gynecology. If you have any symptoms such as abdominal pain, bloating, or changes in bowel habits, it may be beneficial to see a gastroenterologist as well.

- Further Diagnostic Testing: Your healthcare provider may recommend additional tests to determine the underlying cause of the elevated markers. This could include imaging studies such as a CT scan or MRI, and possibly a biopsy if a suspicious mass is identified.

- Comprehensive Evaluation: It is crucial to consider your complete medical history, any symptoms you may be experiencing, and other diagnostic results. Tumor markers can sometimes be elevated due to non-cancerous conditions, so a thorough evaluation is necessary to avoid unnecessary anxiety.

3. Follow-Up:
- After the initial consultation and any additional tests, your healthcare provider will discuss the findings with you and outline a treatment plan if necessary. This may include monitoring the markers over time, further imaging studies, or initiating treatment if a malignancy is confirmed.

4. Emotional Support:
- Receiving abnormal test results can be stressful and anxiety-inducing. It is important to seek support from family, friends, or support groups. Many patients find it helpful to talk about their concerns and feelings during this time.

In summary, your next steps should involve scheduling an appointment with an oncologist or gynecologist to discuss your elevated tumor markers. They will guide you through the necessary diagnostic processes and help you understand the implications of your results. Remember, elevated tumor markers do not definitively indicate cancer, and further testing is essential for an accurate diagnosis.

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