Painful Urination Without Inflammation: A Urology Perspective - Urology

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Painful urination examination shows no inflammation?


Hello Doctor, I would like to provide some recent details to assist you in your assessment.
On May 22, I had unprotected oral sex with a partner and protected intercourse.
On June 5, I experienced some discomfort in my urethra after straining during a bowel movement, but based on past experiences, I thought it was just due to the straining.
The next morning, I noticed a burning sensation while urinating and swelling in the lymph nodes in my groin, so I visited a urologist.
After a urinalysis, the doctor indicated that I had mild inflammation and prescribed a three-day course of antibiotics (I had already been on antibiotics for a week due to a cold prior to this).

On June 8, the burning sensation intensified and became painful, accompanied by a small amount of clear discharge.
I returned to the urologist, and after another urinalysis, the doctor stated there was no inflammation, suggesting that the pain might be due to injury to the corpus cavernosum from sexual activity or masturbation.
I was prescribed a seven-day course of Voren, Doxycycline, and general antibiotics.

Starting June 9, I began to notice hematuria, with pinkish urine at the beginning of urination.
After urinating, I would see fresh blood on the toilet paper, and after some time, blood would also be expelled from the urethra.
Urination remained painful; if the urine was concentrated, I experienced a burning sensation at the base of the penis, and a stabbing pain at the tip.
If the urine was clearer, only the glans would have a stabbing sensation.

On June 13, due to ongoing bleeding and only slight improvement in symptoms, I went to a larger hospital.
I was prescribed Uroprin and underwent urinalysis for bacterial culture, with a follow-up appointment scheduled for next week to review the results.
Since June 13, aside from improvement in hematuria, the stabbing pain and burning sensation during concentrated urination persist.

I would like to ask the doctor:
1.
Is it common for urethritis to cause pain during urination for such an extended period?
2.
Given that the urinalysis results showed mild inflammation and the second urinalysis indicated no inflammatory response, is it normal to still experience pain during urination?
3.
How much longer can I expect to experience pain during urination?
Thank you for your responses, Doctor.

33 sui nanxing, 30~39 year old female. Ask Date: 2023/06/15

Dr. Du Shixi reply Urology


Hello; Regarding your situation: 1.
Is it common for urethritis to cause painful urination for such a long time? -- It can persist if not fully healed.
2.
Is it normal to still experience pain during urination even when urine tests show mild inflammation or no inflammatory response in the second test? -- It is possible, but the pain should improve and symptoms should become milder.
3.
How much longer can I expect to experience pain during urination? -- If you haven't consulted a major hospital, you should do so to rule out other issues.
Additionally, please pay attention to your lifestyle: drink plenty of water, and avoid spicy foods and alcohol.
Wishing you good health.

Reply Date: 2023/06/15

More Info


Painful urination, or dysuria, can be a distressing symptom that may arise from various underlying conditions. Based on your detailed description, it seems that you have been experiencing a complex interplay of symptoms following a series of sexual encounters and subsequent medical evaluations. Let's break down your concerns and provide some insights from a urological perspective.

1. Duration of Painful Urination: Urinary tract infections (UTIs) typically present with symptoms such as burning during urination, increased frequency, and urgency. While many UTIs can resolve with appropriate antibiotic treatment, some cases may persist longer, especially if there are underlying issues such as inflammation or irritation of the urinary tract. In your case, the prolonged nature of your symptoms, despite treatment, suggests that there may be additional factors at play, such as irritation from previous infections, trauma from sexual activity, or even a potential non-infectious cause.

2. Negative Urinalysis with Persistent Symptoms: It is indeed possible to experience pain during urination even when urinalysis results do not indicate active inflammation or infection. This can occur due to several reasons:
- Irritation: The urinary tract can remain sensitive and inflamed after an infection has resolved, leading to ongoing discomfort.

- Trauma: As your doctor suggested, activities such as vigorous sexual intercourse or even aggressive masturbation can lead to microtrauma in the urethra or surrounding tissues, resulting in pain.

- Interstitial Cystitis: This is a chronic condition characterized by bladder pressure, bladder pain, and sometimes pelvic pain, which can mimic UTI symptoms but does not involve an infection.

3. Expected Duration of Symptoms: The timeline for recovery can vary significantly based on the underlying cause. If the pain is due to irritation or trauma, it may take several days to weeks for the symptoms to fully resolve. If there is an underlying condition such as interstitial cystitis, management may require a more prolonged approach, including lifestyle modifications, dietary changes, and possibly medications aimed at reducing bladder inflammation.


Recommendations:
- Follow-Up Care: Since you have already seen a urologist and undergone various tests, it is crucial to maintain open communication with your healthcare provider. If symptoms persist or worsen, consider seeking a second opinion or asking for further diagnostic tests, such as a cystoscopy, which allows direct visualization of the bladder and urethra.


- Symptom Management: In the meantime, you might find relief through:
- Hydration: Drinking plenty of water can help dilute urine and reduce irritation.

- Avoiding Irritants: Stay away from caffeine, alcohol, and spicy foods, which can exacerbate bladder irritation.

- Pain Relief: Over-the-counter pain relievers may help alleviate discomfort.

- Consider Behavioral Factors: If anxiety or stress is contributing to your symptoms, exploring relaxation techniques or counseling may be beneficial.

In conclusion, while painful urination can often be attributed to infections, your case illustrates that persistent symptoms can arise from a variety of causes, including irritation and trauma. It is essential to work closely with your healthcare provider to identify the root cause and develop an effective treatment plan. Your health and comfort are paramount, and addressing these symptoms comprehensively will help you regain your well-being.

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