Low Lipase Levels in Health Check Reports: What You Need to Know - Gastroenterology and Hepatology

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The lipase index in the health check report is low?


Hello, doctor.
I recently received my health check report and found that my fasting lipase level is only 18.
Is this considered abnormal? Thank you.

Yuan, 30~39 year old female. Ask Date: 2023/06/17

Dr. Cai Jinji reply Gastroenterology and Hepatology


Dear Mr.
Yuan,
May I ask if the lipase index is within the normal range? According to our hospital, the normal range is between 13-60 IV/L.
Please also consult with the hospital where the examination was conducted.

Sincerely,
Director Cai Jinji
Department of Hepatobiliary and Gastroenterology
Nantou Hospital

Reply Date: 2023/06/17

More Info


Low lipase levels in health check reports can indeed raise questions about your health, but it's important to interpret these results in context. Lipase is an enzyme primarily produced by the pancreas, and it plays a crucial role in the digestion of fats. Typically, normal lipase levels range from about 10 to 140 units per liter, depending on the laboratory and the specific testing methods used.
In your case, a lipase level of 18 is on the lower end of the spectrum. However, low lipase levels do not necessarily indicate a health problem. There are several factors that can lead to low lipase levels, including:
1. Nutritional Status: If you are underweight or malnourished, your body may produce lower amounts of lipase. This is particularly relevant if you have been on a restrictive diet or have experienced significant weight loss.

2. Medications: Certain medications can affect lipase levels. For example, some medications used to treat high cholesterol or other conditions may lower lipase production.

3. Pancreatic Function: While low lipase levels can sometimes indicate pancreatic insufficiency, this is more commonly associated with elevated levels of lipase. If your pancreas is not producing enough enzymes, you might see low levels of lipase, but this is less common.

4. Physiological Variability: It's also important to consider that lab results can vary from test to test due to factors such as hydration status, time of day, and even the specific assay used by the laboratory.

5. Other Health Conditions: Conditions such as chronic pancreatitis or cystic fibrosis can lead to low lipase levels, but these are typically accompanied by other symptoms or abnormal lab results.

Given that your lipase level is low but not critically so, and assuming you do not have any symptoms such as abdominal pain, weight loss, or digestive issues, it may not be a cause for immediate concern. However, it is essential to monitor your overall health and any symptoms you may experience.
If you have any ongoing health issues, or if you are experiencing symptoms that concern you, it would be prudent to follow up with your healthcare provider. They may recommend further testing or a referral to a specialist, such as a gastroenterologist, to evaluate your pancreatic function more thoroughly.

In summary, while a low lipase level can be indicative of certain health issues, it is not inherently alarming. It is crucial to consider the broader clinical picture, including any symptoms you may have and other lab results. Regular monitoring and open communication with your healthcare provider will help ensure that any potential issues are addressed promptly and appropriately.

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