ST, T Wave Abnormalities and Prolonged QT Interval Risks - Cardiology

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ST and T wave abnormalities; prolonged QT interval?


Hello, Director: My wife is 75 years old.
Last month, on a certain day, she became lethargic and unresponsive after taking an extra "Jingdeke Epilepsy Tablet." She was taken to the emergency room of a hospital, where an electrocardiogram (ECG) was performed.
The results showed: Normal sinus rhythm, nonspecific ST and T wave abnormalities, prolonged QT interval, and abnormal ECG.
The hospital did not suggest any further tests, but the findings seem concerning.
Could you please advise if this issue is serious? Thank you for your time in explaining...

Mr. Li, 70~79 year old female. Ask Date: 2023/06/19

Dr. Wu Xueming reply Cardiology


Abnormalities in the electrocardiogram (ECG) need to be interpreted in conjunction with the clinical symptoms and the graphical representation.
It is recommended to consult a cardiologist in an outpatient setting.

Reply Date: 2023/06/19

More Info


The findings from your wife's electrocardiogram (ECG) indicate a normal sinus rhythm, nonspecific ST and T wave abnormalities, and a prolonged QT interval. Each of these components can provide important insights into her cardiac health, especially considering her age and recent medical history.


Understanding the Components:
1. Normal Sinus Rhythm: This indicates that the heart is beating in a regular pattern, which is a positive sign. It suggests that the electrical impulses that control the heartbeat are functioning normally.

2. Nonspecific ST and T Wave Abnormalities: These abnormalities can be indicative of various conditions, including ischemia (reduced blood flow to the heart), electrolyte imbalances, or even the effects of medications. The term "nonspecific" means that while there are changes present, they do not point to a specific diagnosis. This can sometimes be benign, but it warrants further investigation, especially in older adults or those with risk factors for heart disease.

3. Prolonged QT Interval: The QT interval measures the time it takes for the heart's ventricles to depolarize and repolarize after each heartbeat. A prolonged QT interval can increase the risk of serious arrhythmias, including Torsades de Pointes, which can lead to fainting or even sudden cardiac death. The normal range for QTc (corrected QT interval) is generally considered to be less than 440 ms for men and less than 460 ms for women. A QTc of over 450 ms is considered prolonged, and values above 500 ms are particularly concerning.


Clinical Significance:
Given your wife's age and the context of her recent episode of altered consciousness after taking a medication, the findings on her ECG should not be taken lightly. While the normal sinus rhythm is reassuring, the combination of nonspecific ST and T wave changes along with a prolonged QT interval raises concerns that should be addressed.


Recommendations:
1. Follow-Up with a Cardiologist: It is crucial to consult a cardiologist who can interpret the ECG in the context of her overall health, symptoms, and any medications she may be taking. They may recommend further testing, such as a Holter monitor (24-hour ECG) or an echocardiogram, to assess her heart function more thoroughly.

2. Medication Review: Certain medications can prolong the QT interval. It would be beneficial to review all medications she is currently taking with her healthcare provider to determine if any adjustments are necessary.

3. Monitoring Symptoms: Keep a close watch on any symptoms such as palpitations, dizziness, or fainting spells. If any of these occur, seek immediate medical attention.

4. Lifestyle Considerations: Encourage a heart-healthy lifestyle, including a balanced diet, regular physical activity (as tolerated), and avoiding stimulants such as caffeine and certain over-the-counter medications that may exacerbate QT prolongation.


Conclusion:
In summary, while the normal sinus rhythm is a positive aspect of your wife's ECG, the nonspecific ST and T wave abnormalities combined with a prolonged QT interval warrant further evaluation. It is essential to work closely with her healthcare team to monitor her heart health and address any potential risks. Early intervention can significantly improve outcomes, especially in older adults with complex medical histories.

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