Low Blood Pressure and Heart Rate Changes After Medication - Cardiology

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Blood pressure issues?


Hello, Doctor.
I apologize for asking another question regarding a recent issue.
My usual blood pressure is around 120/75.
Recently, I've been taking a heart rhythm medication in the morning, around 11 AM, for about three weeks.
However, for the past two days, at around 11 PM, which is over 12 hours after taking the medication, my blood pressure has been around 105/59.
This low blood pressure shouldn't be related to the heart rhythm medication, right? Since my usual blood pressure is on the higher side, between 120 and 130, this is the first time I've measured around 100, and I'm unsure if there is any problem.
Additionally, my heart rate has been slower over the past three days; it usually averages around 75 but is now between 58 and 65.
Is this a sign of autonomic nervous system imbalance, with sympathetic nervous system activity being high at times and parasympathetic nervous system activity being low at others? Doctor, could this pose any risks? I've also been experiencing dizziness at night, and I'm unsure if it's related to the autonomic nervous system or something else.
In the mornings, after taking the heart rhythm medication, my blood pressure is sometimes around 115-120, but in the evenings, after the medication wears off, my blood pressure and heart rate are even lower.
Is this normal? I'm hesitant to increase the evening dosage of the heart rhythm medication, so I only take it in the morning.
I apologize for troubling you again, and thank you for your help.
Take care.

Nìngmíng, 20~29 year old female. Ask Date: 2023/07/02

Dr. He Dongjin reply Cardiology


Hello, basically we are human, and fluctuations in blood pressure and heart rate are normal.
Occasional headaches and dizziness are also inevitable; this does not necessarily indicate any danger.
People are not that fragile.
Just relax and go on with life.
Changhua Hospital cares about you.

Reply Date: 2023/07/02

More Info


Understanding low blood pressure and heart rate changes after medication is crucial, especially for individuals who are on medications that can affect cardiovascular function. In your case, it seems that you have been experiencing lower blood pressure readings and a slower heart rate after starting a new medication for heart rhythm management. Let's break down the potential causes and implications of these changes.

Firstly, it's important to recognize that blood pressure and heart rate are regulated by a complex interplay of the autonomic nervous system, hormones, and various medications. The medication you mentioned, often referred to as a "heart rhythm pill," may have effects on both heart rate and blood pressure. While you noted that your blood pressure has typically been around 120/75 mmHg, the recent readings of 105/59 mmHg indicate a drop that could be concerning, especially if accompanied by symptoms like dizziness.

Low blood pressure (hypotension) can occur for several reasons, including dehydration, blood loss, or the effects of medications. In your case, since you have been on the medication for about three weeks, it is possible that your body is still adjusting to the new medication, or that the medication itself is contributing to the lower blood pressure. It is also worth noting that some heart rhythm medications can lead to bradycardia (a slower than normal heart rate), which you have also experienced with rates dropping to 58-65 bpm.

The relationship between blood pressure and heart rate is complex. Generally, when blood pressure drops, the body may respond by increasing heart rate to maintain adequate blood flow to vital organs. However, in some cases, particularly with certain medications, both blood pressure and heart rate can decrease simultaneously. This can lead to symptoms such as dizziness or lightheadedness, particularly when standing up quickly (orthostatic hypotension).

Regarding your concern about autonomic nervous system fluctuations, it is indeed possible that your symptoms could be related to dysregulation of the autonomic nervous system. This system controls involuntary bodily functions, including heart rate and blood pressure. An imbalance between the sympathetic (fight or flight) and parasympathetic (rest and digest) systems can lead to variations in heart rate and blood pressure, contributing to feelings of dizziness or faintness.

As for the timing of your blood pressure readings, it is not uncommon for blood pressure to fluctuate throughout the day, often being lower in the evening or after the effects of medication have worn off. If you find that your blood pressure and heart rate are consistently lower in the evening, it may be worth discussing with your healthcare provider whether adjustments to your medication regimen are necessary. It is essential to ensure that you are not experiencing adverse effects from the medication, especially if you are feeling unwell.

In terms of safety, consistently low blood pressure and heart rate can pose risks, particularly if they lead to inadequate blood flow to the brain and other vital organs. Symptoms like dizziness, especially if they are persistent, should not be ignored. It is advisable to consult with your healthcare provider about your symptoms, medication timing, and any necessary adjustments to your treatment plan.

In summary, while low blood pressure and heart rate changes can be a normal response to medication, they can also indicate a need for further evaluation. Monitoring your symptoms closely and maintaining open communication with your healthcare provider will be key in managing your condition effectively. If you continue to experience dizziness or other concerning symptoms, do not hesitate to seek medical advice.

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