Thyroid issues?
Two years ago, during my pregnancy, I had a thyroid report showing TSH < 0.005 and T4 1.570, which were within the normal range.
At that time, my obstetrician mentioned that it might be related to the pregnancy.
Should I have any special examinations for this? My mother had thyroid surgery when she was younger, and I previously had a blood test showing platelet count of 444, MCV 75.8, MCH 22.3, and MCHC 29.4.
Does this indicate thalassemia? My parents both claim they do not have thalassemia.
🥲
Zhou, 30~39 year old female. Ask Date: 2023/07/05
Dr. Cao Guotao reply Obstetrics and Gynecology
Hello, you can consult an endocrinologist regarding thyroid issues.
An MCV less than 80 may indicate thalassemia trait; as long as your husband is normal, there is no need to worry.
Wishing you good health!
Reply Date: 2023/07/05
More Info
Thyroid issues during pregnancy are a significant concern, as they can impact both maternal health and fetal development. Your previous thyroid test results indicate a very low TSH level (<0.005), which suggests hyperthyroidism. While it is true that pregnancy can alter thyroid hormone levels due to increased demand and changes in metabolism, it is essential to monitor these levels closely, especially given your family history of thyroid surgery and your mother's past thyroid issues.
In general, thyroid function tests during pregnancy should be interpreted with caution. The normal reference ranges for TSH and thyroid hormones can shift during pregnancy, particularly in the first trimester. The American Thyroid Association recommends that TSH levels should ideally be maintained between 0.1 and 2.5 mIU/L in the first trimester for optimal fetal development. If your TSH is significantly lower than this range, it may warrant further investigation.
Given your history of thyroid surgery in your mother, it is prudent to discuss your thyroid function with your obstetrician or an endocrinologist. They may recommend additional testing, such as free T4 and thyroid antibodies, to assess your thyroid function comprehensively. If hyperthyroidism is confirmed, treatment options may include antithyroid medications, which are generally considered safe during pregnancy but should be managed carefully by a healthcare provider.
Regarding your blood test results indicating a platelet count of 444, along with the mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), and mean corpuscular hemoglobin concentration (MCHC), it is essential to consider these values in the context of your overall health and symptoms. A platelet count of 444 is within the normal range, but the MCV of 75.8 suggests microcytic anemia, which could be indicative of iron deficiency or thalassemia, including Mediterranean anemia (thalassemia trait). However, since you mentioned that your parents do not have a history of Mediterranean anemia, it may be worth discussing with your healthcare provider to determine if further testing for iron levels or hemoglobin electrophoresis is necessary.
In summary, it is crucial to maintain open communication with your healthcare provider regarding your thyroid function and any potential anemia. Regular monitoring and appropriate testing can help ensure both your health and the health of your baby during pregnancy. If you experience any symptoms such as fatigue, weight changes, or palpitations, or if you have concerns about your thyroid levels or blood counts, do not hesitate to seek further evaluation. Early intervention can be key in managing any potential complications during pregnancy.
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