HPV Testing Accuracy for Urological Concerns - Urology

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Cauliflower issue


Hello doctor, I would like to ask about the accuracy of urine testing for HPV.
I had a self-paid test done at a lab using the first morning urine, and it came back negative.
However, recently I noticed two small white spots on both sides of the glans corona, near the lower middle area.
I'm not sure if they have been there before.
After researching online, they look similar to pearly penile papules, but I'm still worried that they might be genital warts.
😥

Danxin de ren, 30~39 year old female. Ask Date: 2023/07/12

Dr. Chen Jiansheng reply Urology


Please seek medical attention.

Reply Date: 2023/07/12

More Info


When it comes to HPV testing, particularly in the context of urological concerns, it's important to understand the nuances of the testing methods and their accuracy. HPV, or human papillomavirus, is a common sexually transmitted infection that can lead to various health issues, including genital warts (often referred to as "cauliflower-like" growths) and, in some cases, cancers.

Accuracy of Urine Testing for HPV
Urine testing for HPV is not as widely used or validated as other methods, such as cervical swabs or biopsies. While urine tests can detect the presence of HPV, their sensitivity and specificity may not be as high as those of other testing methods. This means that while a negative urine test can provide some reassurance, it does not completely rule out the possibility of an HPV infection, especially if you have visible symptoms or lesions.

In your case, the fact that your urine test came back negative is a positive sign, but it doesn't eliminate the need for further evaluation, especially given the presence of small white spots on your glans (the head of the penis). These spots could be pearly penile papules, which are harmless and common, or they could be a sign of a different condition, including genital warts caused by HPV.


Understanding the Symptoms
The appearance of small white spots can be concerning, and it's understandable to worry about the possibility of HPV-related lesions. Genital warts typically appear as small, flesh-colored or white bumps that can be raised or flat. They may cluster together, resembling cauliflower. However, not all white spots are warts; as you mentioned, they could also be pearly penile papules, which are normal anatomical variations and not indicative of an infection.


Recommendations for Further Evaluation
Given your concerns and the presence of these spots, it would be advisable to consult a healthcare provider, preferably a urologist or dermatologist, who can perform a physical examination. They may recommend a visual inspection and possibly a biopsy if there is any doubt about the nature of the lesions.
Additionally, if you are sexually active, discussing your sexual health and any potential risks with your healthcare provider is crucial. They may suggest further testing or monitoring, especially if you have multiple sexual partners or if you have had unprotected sex.


HPV and Its Implications
It's important to remember that while many HPV infections resolve on their own due to the body's immune response, some strains can lead to more serious health issues. Regular check-ups and screenings are essential, particularly if you have risk factors for HPV-related diseases. Vaccination against HPV is also a highly effective preventive measure and is recommended for individuals up to age 26, and in some cases, up to age 45.


Conclusion
In summary, while your urine test for HPV was negative, it is not definitive, especially in the presence of new symptoms. Consulting a healthcare professional for a thorough evaluation is the best course of action. They can provide you with a clearer understanding of your situation and guide you on the next steps, whether that involves further testing or reassurance regarding your symptoms. Remember, maintaining open communication with your healthcare provider about your sexual health is key to managing any concerns effectively.

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