Can I Continue Using Clindamycin Gel for Acne? Expert Advice - Dermatology

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Hello doctor, after using clindamycin gel on my acne, I experienced mild itching, redness, and hyperkeratosis (it feels rough) around the acne.
Can I continue using it? Also, what other skin conditions can this gel be used for?

Niming, 10~19 year old female. Ask Date: 2023/07/16

Dr. Wu Yuxin reply Dermatology


If you experience any discomfort or concerns, it is advisable to stop the medication and discuss it with your prescribing physician.

Reply Date: 2023/07/16

More Info


Clindamycin gel is a topical antibiotic commonly used to treat acne. It works by inhibiting bacterial growth and reducing inflammation in the skin. However, as with any medication, it can have side effects, and your experience of mild itching, redness, and roughness of the skin (keratinization) may indicate a reaction to the medication.

Given your symptoms, it is essential to evaluate whether you should continue using Clindamycin gel. Mild irritation can be a common side effect, but if the symptoms persist or worsen, it may be a sign of an allergic reaction or sensitivity to the medication. In such cases, it is advisable to discontinue use and consult with a healthcare professional or dermatologist. They can assess your skin condition and determine whether the symptoms are indeed related to the gel or if there might be another underlying issue.

In terms of other skin conditions, Clindamycin gel is primarily indicated for acne vulgaris. However, it may also be used off-label for other bacterial skin infections, such as folliculitis or certain types of dermatitis, where bacterial infection is suspected. It is important to note that while Clindamycin can be effective against certain bacteria, it is not suitable for all skin conditions. For example, it is not effective against viral or fungal infections.

If you are experiencing side effects, consider the following steps:
1. Discontinue Use: Stop applying the gel until you can consult with a healthcare provider. This will help prevent further irritation.

2. Consult a Dermatologist: Schedule an appointment with a dermatologist who can evaluate your skin and provide tailored advice. They may suggest alternative treatments for your acne or recommend a different formulation that may be less irritating.

3. Patch Test: If you are advised to try Clindamycin again or another topical treatment, consider performing a patch test on a small area of skin to check for any adverse reactions before applying it to larger areas.

4. Moisturize: If your skin feels dry or irritated, using a gentle, non-comedogenic moisturizer can help soothe the skin. Look for products that are fragrance-free and formulated for sensitive skin.

5. Monitor Symptoms: Keep track of any changes in your skin condition, including the severity of the itching, redness, or roughness. This information will be helpful for your healthcare provider.

In summary, while Clindamycin gel can be effective for treating acne, your current symptoms suggest that it may not be suitable for you at this time. Consulting with a dermatologist will provide you with the best course of action and alternative treatment options tailored to your skin's needs. Remember, it is crucial to listen to your body and seek professional advice when experiencing adverse reactions to any medication.

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