Concerns About Side Effects of Clonazepam for Sleep Disorders - Psychiatry

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Inquiry about the side effects of tranquilizers?


Hello, Doctor.
I have been diagnosed with circadian rhythm disorder (difficulty falling asleep) and unspecified anxiety disorder.
I have a medication history of 3 years, originally taking Remeron 1, Trazodone 2, Ativan 2, and Zolpidem 1.5.
After my follow-up appointment on Monday, my doctor changed Zolpidem to Diazepam 2 due to concerns about potential dependence on the medication.
However, after just one day of taking it, I found that I still could not sleep until dawn, and I also experienced skin itching.
I would like to ask the doctor if I should immediately stop the medication and return for a prescription change due to the itching, or would it be better to wait until my next appointment next week to discuss this?

Zhou, 20~29 year old female. Ask Date: 2023/07/18

Dr. Qiu Junda reply Psychiatry


Hello.
Since it is uncertain whether the skin itching is caused by the change to the sedative medication, it is recommended to first consult a dermatologist for evaluation and treatment.
This will help clarify the cause and improve the condition.

Reply Date: 2023/07/18

More Info


When it comes to the use of Clonazepam (Klonopin) and other medications for sleep disorders and anxiety, it's essential to understand both the therapeutic effects and potential side effects. Clonazepam is a benzodiazepine that is commonly prescribed for anxiety and seizure disorders, but it is also sometimes used off-label for sleep issues. However, it is crucial to be aware of the implications of long-term use and the side effects that may arise.

In your case, you have been diagnosed with circadian rhythm disorder and unspecified anxiety disorder, and you have a history of medication use for these conditions. The recent change from your previous medication (Uremin) to a different benzodiazepine (Anxiolytic) raises some concerns, especially since you experienced difficulty sleeping and skin itching after just one dose.

Firstly, it's important to address the skin itching you mentioned. Skin reactions can occur with many medications, including benzodiazepines. While itching may not be a common side effect of Clonazepam or Anxiolytic, it could indicate an allergic reaction or sensitivity to the medication. If the itching is severe or accompanied by other symptoms such as rash, swelling, or difficulty breathing, it is advisable to stop the medication immediately and seek medical attention. If the itching is mild, you might consider discussing it with your doctor at your next appointment, but it is always better to err on the side of caution when it comes to potential allergic reactions.

Regarding your sleep difficulties, benzodiazepines like Clonazepam can be effective for short-term management of insomnia, but they are not typically recommended for long-term use due to the risk of dependence and tolerance. This means that over time, you may find that the medication becomes less effective, or you may need higher doses to achieve the same effect. Additionally, stopping benzodiazepines suddenly can lead to withdrawal symptoms, including increased anxiety and sleep disturbances.

Your doctor’s concern about potential dependence is valid, especially given your history of medication use. It might be beneficial to explore non-benzodiazepine options for managing your sleep and anxiety, such as selective serotonin reuptake inhibitors (SSRIs) or other classes of medications that have a lower risk of dependence. Cognitive-behavioral therapy (CBT) for insomnia is another effective treatment that can help address the underlying issues contributing to your sleep difficulties without the need for medication.

In summary, if you are experiencing skin itching after starting a new medication, it is essential to consult with your healthcare provider as soon as possible. They can evaluate your symptoms and determine whether you should discontinue the medication or try an alternative treatment. Additionally, discussing your ongoing sleep issues and the potential for medication dependence with your doctor can help you find a more sustainable and effective treatment plan. Always prioritize open communication with your healthcare provider to ensure that your treatment aligns with your health needs and concerns.

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