Can Multivitamins Be Safely Taken with Psychiatric Medications? - Psychiatry

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Can individuals with neurosis take multivitamins?


Hello, Doctor: I am currently taking medication, which includes Fludiazepam (Erispan) 0.25 mg, Propranolol 10 mg, and Paroxetine (Seroxat) 20 mg.
I would like to ask if taking a multivitamin (such as "Centrum," one tablet daily) after noon, during a time when I am not taking my medications, would have any adverse effects.
Thank you!

josephy, 30~39 year old female. Ask Date: 2003/12/31

Dr. Liu Junxian reply Psychiatry


Hello Josephy: There are no interactions between Centrum and the medications you mentioned.
It is best to take them separately, and if possible, avoid taking them at night, as some individuals may experience sleep disturbances after taking them.

Reply Date: 2003/12/31

More Info


Taking multivitamins alongside psychiatric medications is a common concern for many patients. In your case, you are currently prescribed Fludiazepam (Erispan), Propranolol, and Paroxetine (Seroxat). Let's break down the potential interactions and safety of combining these medications with multivitamins.

1. Fludiazepam (Erispan): This medication is a benzodiazepine used primarily for anxiety and sleep disorders. Generally, there are no significant interactions between multivitamins and benzodiazepines. However, it's essential to avoid any supplements that may have sedative effects, as they could potentially enhance the sedative properties of Fludiazepam.

2. Propranolol: This is a beta-blocker commonly used for anxiety, hypertension, and other cardiovascular conditions. Propranolol can interact with certain minerals, particularly magnesium and calcium, which are often found in multivitamins. High doses of these minerals may affect the absorption of Propranolol, potentially reducing its effectiveness. Therefore, if your multivitamin contains these minerals, it’s advisable to space out the timing of your doses.

3. Paroxetine (Seroxat): This is a selective serotonin reuptake inhibitor (SSRI) used to treat depression and anxiety disorders. There are no direct contraindications for taking multivitamins with Paroxetine. However, some vitamins, particularly B vitamins, can influence mood and energy levels, which might affect how you feel while on Paroxetine.
4. General Considerations: When taking any medication, it’s crucial to consider the overall balance of nutrients in your diet. Some psychiatric medications can lead to nutrient deficiencies over time. For instance, SSRIs like Paroxetine may affect levels of certain vitamins and minerals, such as B vitamins and magnesium, which are essential for mental health. Therefore, a multivitamin could potentially be beneficial in addressing these deficiencies.

5. Timing: As you mentioned wanting to take your multivitamin in the afternoon when you are not taking your medications, this is a good strategy. Taking the multivitamin at a different time from your medications can help minimize any potential interactions and ensure that you are getting the full benefit of both.

6. Consultation with Healthcare Provider: It is always best to consult with your healthcare provider or a pharmacist before adding any new supplements to your regimen. They can provide personalized advice based on your specific health needs, current medications, and any other underlying health conditions you may have.

In conclusion, taking a multivitamin like "善存" (Centrum) while on Fludiazepam, Propranolol, and Paroxetine is generally considered safe, provided you are mindful of the timing and the specific ingredients in the multivitamin. Always prioritize open communication with your healthcare provider to ensure that your treatment plan is safe and effective.

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