Enlarged Lymph Nodes: Causes and When to Seek Help - Internal Medicine

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Lymphadenopathy Infection Issues


Hello Doctor, I would like to ask you some questions: About six months ago, I noticed swelling in the lymph nodes on both sides of my groin.
Almost every node in that area has enlarged, with a few becoming elongated, measuring approximately 1 to 2 centimeters.
Interestingly, I consulted a general surgeon who said that the nodes felt normal in structure and that as long as they haven't continued to grow or suddenly increased in size, there is not much to worry about (they haven't changed in size over the past six months).
Additionally, this week I felt a slight pain in the lymph nodes in my groin (not sure if it's just psychological?).
A few days ago, I noticed a similar condition in the lymph nodes on both sides of my neck, but it seems there are not as many nodes there (perhaps because there are fewer lymph nodes in the neck?).
I also visited an ENT specialist who mentioned that there is slight swelling.
Furthermore, this week I have felt a bit of pain in the groin lymph nodes, and my overall condition has been feeling more fatigued (not sure if it's due to lack of sleep and going to bed late).
Therefore, I am uncertain if this is a symptom or simply due to fatigue.
I would like to ask you, could my condition indicate an infection? What tests should I undergo? Since I tend to be more sensitive, the doctor suggested I could see an infectious disease specialist.
However, the way the doctor spoke made it seem like getting checked would provide me with more peace of mind, otherwise, I might overthink things.
Should I observe my condition for a while longer, or should I go for a check-up now? Thank you for your response and clarification!

Niming, 20~29 year old female. Ask Date: 2023/07/19

Dr. Lin Wufu reply Internal Medicine


Hello, multiple enlarged lymph nodes usually indicate that there is some condition in the body, ranging from systemic infections, rheumatologic and autoimmune diseases, to hematologic malignancies.
Therefore, it is recommended to visit an infectious disease clinic as soon as possible for relevant examinations and diagnosis!

Reply Date: 2023/07/19

More Info


Enlarged lymph nodes can be a source of concern for many individuals, especially when they are noticed in areas such as the groin or neck. Your situation, where you have observed bilateral enlargement of the lymph nodes in the groin and some tenderness, along with recent changes in the neck, warrants careful consideration.

Firstly, it is important to understand that lymph nodes are part of the immune system and can become enlarged for various reasons. Common causes include infections (viral or bacterial), inflammatory conditions, and malignancies. In your case, the fact that the lymph nodes have not significantly changed in size over the past six months is a reassuring sign, as persistent enlargement or rapid growth is often more concerning.

The tenderness you are experiencing in the groin lymph nodes could be related to several factors. It might be a sign of a mild infection or inflammation, especially if you have been feeling more fatigued than usual. Fatigue can stem from various causes, including lack of sleep, stress, or even underlying infections. However, it is also essential to note that anxiety and stress can manifest physically, leading to heightened awareness of bodily sensations, which may contribute to your perception of pain.

Given that you have also noticed some enlargement in the neck lymph nodes, it is prudent to consider a few possibilities. The neck lymph nodes can swell in response to infections, such as a cold or throat infection, or due to other inflammatory processes. The fact that an ENT specialist noted some enlargement is worth noting, but without additional symptoms (like fever, significant pain, or systemic symptoms), it may not be an immediate cause for alarm.

In terms of next steps, it is advisable to follow the guidance of your healthcare provider. If they suggested seeing an infectious disease specialist, it could be beneficial for peace of mind and to rule out any underlying infections that may not have been identified yet. Tests that may be considered include blood tests to check for signs of infection or inflammation, imaging studies (like an ultrasound or CT scan) to further evaluate the lymph nodes, or even a biopsy if there is a suspicion of malignancy.

Monitoring your symptoms is also crucial. If you notice any changes, such as increased size of the lymph nodes, new symptoms (like fever, night sweats, or unexplained weight loss), or if the pain worsens, you should seek medical attention promptly.
In summary, while the current state of your lymph nodes does not appear to be alarming, it is essential to remain vigilant. Regular follow-ups with your healthcare provider, maintaining open communication about any new symptoms, and possibly consulting with an infectious disease specialist can help ensure that any underlying issues are addressed. Your health and peace of mind are paramount, so do not hesitate to seek further evaluation if you feel it is necessary.

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