Can Dried HIV Blood Reactivate When Exposed to Fresh Blood? - Internal Medicine

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HIV infection


Hello, doctor.
I am the one who previously inquired about #198925.
I would like to ask again, if blood containing the HIV virus has dried, is there a possibility that the virus could become active again if it comes into contact with a wound or fresh blood? Thank you, doctor.

Lin, 20~29 year old female. Ask Date: 2023/07/26

Dr. Liao Zhongxin reply Internal Medicine


Hello, no, unless there is further exposure to fresh blood, there is a chance of infection.

Reply Date: 2023/07/26

More Info


When it comes to the question of whether dried HIV blood can reactivate when exposed to fresh blood, it’s important to understand the biology of the HIV virus and how it behaves outside the human body. HIV, or Human Immunodeficiency Virus, is a fragile virus that does not survive long outside its host. Once blood containing HIV dries, the virus becomes inactive and cannot cause infection.

HIV is primarily transmitted through specific bodily fluids, including blood, semen, vaginal fluids, rectal fluids, and breast milk. The virus requires a certain concentration to be infectious, and once the blood has dried, the concentration of the virus diminishes significantly. Studies have shown that HIV can survive in dried blood for a limited time, typically only a few hours to a few days, depending on environmental conditions such as temperature and humidity. However, the infectious potential of the virus decreases rapidly once the blood has dried.

In your scenario, if dried HIV-infected blood comes into contact with fresh blood or an open wound, the dried virus cannot reactivate or become infectious. The dried blood does not contain viable HIV particles capable of initiating an infection. The only way for HIV to be transmitted is through direct contact with fresh, infectious bodily fluids from an HIV-positive individual.

If you were to come into contact with fresh blood that is known to be HIV-positive, there would be a risk of transmission if that blood were to enter your bloodstream through an open wound. However, the dried blood itself does not pose a risk of reactivating the virus or causing infection.

It is also worth noting that the risk of HIV transmission is influenced by several factors, including the viral load of the HIV-positive individual (the amount of virus present in their blood), the presence of other sexually transmitted infections, and the type of exposure (e.g., whether it involves a cut, mucous membrane, or other means of entry into the body).

In summary, dried HIV blood cannot reactivate when exposed to fresh blood. The virus becomes inactive once the blood dries, and the risk of transmission only arises from direct contact with fresh, infectious bodily fluids. If you have concerns about potential exposure to HIV or any other infectious disease, it is advisable to consult a healthcare professional for further evaluation and possible testing. Regular testing and awareness of one’s HIV status are essential components of maintaining health and preventing the spread of HIV.

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