Should You Continue Using Suppositories After Two Days of No Dissolution? - Obstetrics and Gynecology

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If the two suppositories have not dissolved after two days, should I insert another one on the third day?


After using the suppository for two consecutive days without any discharge, I inserted my finger to a depth of one finger and felt two un-dissolved suppositories that are still semi-solid deep in the vagina (about one finger's depth).
Should I insert another one on the third night? I have been using the medication for the fourth week, and there is still a thick white discharge deep inside...
it seems unable to be expelled...
Thank you for your response.

Niming, 40~49 year old female. Ask Date: 2023/07/27

Dr. Lin Manying reply Obstetrics and Gynecology


Hello, Miss: If the medication is in solid form, it is recommended to moisten it with warm water before insertion.
You should continue to insert it on the third night as well.
Additionally, if there are still secretions in the deep part of the vagina that cannot be expelled after using the medication, please return to the outpatient clinic for further management.
The Hualien Hospital of the Ministry of Health and Welfare cares about your health.

Reply Date: 2023/07/27

More Info


When it comes to the use of suppositories, particularly in the context of vaginal medications, it is important to understand how these medications work and what to do if they do not dissolve as expected. Suppositories are designed to melt or dissolve at body temperature, allowing the active ingredients to be absorbed into the bloodstream or local tissues. If you have been using a suppository for two days without any sign of dissolution, there are several factors to consider.

First, the formulation of the suppository can affect its dissolution. Some suppositories may be designed to dissolve slowly, while others are meant to dissolve quickly. If you are using a medication that is supposed to dissolve rapidly and it has not, this could indicate an issue with the product itself or with how it is being used.
Second, the insertion technique can also play a role. It is crucial to insert the suppository deep enough into the vaginal canal to ensure that it is not just sitting at the entrance, where it may be more likely to remain intact. However, if you have already inserted the suppository properly and it has not dissolved, it may be a sign of a problem.

Given that you have found two suppositories still intact after two days, it is advisable to consult with your healthcare provider before continuing with the treatment. They can assess whether the medication is appropriate for you and if there are any underlying issues that need to be addressed. It is also important to discuss any persistent symptoms you may be experiencing, such as the thick white discharge you mentioned, as this could indicate an infection or other condition that may require different treatment.

In general, if a suppository does not dissolve after a reasonable amount of time, it is not advisable to continue using it without medical guidance. Continuing to use a medication that is not being absorbed properly could lead to ineffective treatment and may prolong any underlying issues you are experiencing.

In summary, if you have not seen any dissolution of the suppository after two days, it is best to refrain from using another one until you have consulted with your healthcare provider. They can provide personalized advice based on your specific situation and help determine the best course of action for your health. Always prioritize open communication with your healthcare provider regarding any concerns or unusual experiences with medications.

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