Managing Post-Operative Vomiting After Biliary Enteric Bypass Surgery - Surgery

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Pancreatic cancer, biliary-enteric anastomosis?


My mother, 56 years old, is in the late stages of pancreatic cancer.
Due to a bile duct obstruction, she underwent a biliary-enteric anastomosis last month.
A week after the surgery, she began experiencing vomiting symptoms, even after consuming only liquids.
The current doctor believes that the high position of the bypass surgery is causing her to have digestive issues, while another doctor thinks that the small intestine may not be able to accept bile, leading to these symptoms.
What are some potential solutions for this condition? We are truly at a loss as to why her situation has developed this way, especially since an endoscopy showed no signs of obstruction in the intestines.
Thank you.

Alice, 30~39 year old female. Ask Date: 2023/07/27

Dr. Chen Jiaming reply Surgery


Your mother's condition is quite complex, and there are many potential reasons for postoperative vomiting.
It is advisable to consult her primary physician to see if they can arrange for an upper gastrointestinal series (UGI series) or a small bowel series to further investigate whether there are any structural issues causing the vomiting.
Additionally, since she has undergone bowel diversion surgery, it is crucial that after consuming liquid diets, she must remain upright or seated for a certain period before lying down.
Otherwise, there is a high risk of fluid retention in the stomach, which can lead to gastroesophageal reflux and bile vomiting.
Furthermore, it is recommended to consider some self-paid potent antiemetic medications to help suppress central vomiting.
I hope this information provides you with some guidance.

Reply Date: 2023/07/27

More Info


Managing post-operative vomiting after biliary enteric bypass surgery can be quite challenging, especially in patients with complex conditions such as advanced pancreatic cancer. In your mother's case, the vomiting that began a week after the surgery could be attributed to several factors related to the surgical procedure and her underlying health condition.

Firstly, it's important to understand that biliary enteric bypass surgery is performed to relieve biliary obstruction, often caused by tumors or strictures. This procedure reroutes bile flow directly into the intestine, bypassing the obstructed area. Post-operative vomiting can occur due to several reasons:
1. Delayed Gastric Emptying: After surgery, the stomach may take longer to empty its contents into the small intestine. This can lead to feelings of fullness, nausea, and vomiting. This condition is often temporary and may improve as the digestive system adjusts to the changes.

2. Bile Salt Malabsorption: Since bile is essential for fat digestion, any disruption in bile flow can lead to malabsorption. If the small intestine is not able to adequately process bile, it can result in nausea and vomiting. This is particularly relevant if the bypass has altered the normal flow of bile.

3. Dietary Changes: Post-operative dietary restrictions often include a transition to a liquid diet, which can be difficult for some patients. If your mother is struggling to tolerate even clear liquids, it may indicate that her digestive system is not adjusting well to the changes.

4. Nausea from Medications: Sometimes, medications prescribed post-operatively for pain or to prevent infection can cause nausea and vomiting. It's essential to review her medication list with her healthcare provider to determine if any adjustments are needed.

5. Psychological Factors: The stress of undergoing major surgery and the diagnosis of cancer can also contribute to gastrointestinal symptoms. Anxiety and depression can exacerbate nausea and vomiting.

Given these potential causes, here are some management strategies that may help alleviate your mother's symptoms:
- Gradual Diet Progression: If she is currently on a clear liquid diet, it may be beneficial to gradually introduce bland, low-fat foods as tolerated. Foods like bananas, rice, applesauce, and toast (often referred to as the BRAT diet) can be easier on the stomach.

- Hydration: Ensuring she stays hydrated is crucial. If she is unable to keep fluids down, consider electrolyte solutions or intravenous hydration if necessary.

- Medications: Anti-nausea medications (antiemetics) can be prescribed to help control vomiting. Discuss with her healthcare provider about the possibility of using medications like ondansetron or metoclopramide.

- Small, Frequent Meals: Instead of three large meals, encourage her to eat small, frequent meals throughout the day. This can help reduce the burden on her digestive system.

- Positioning: After eating, keeping her upright for at least 30 minutes may help with digestion and reduce the likelihood of vomiting.

- Follow-Up Care: Since her symptoms are persistent, it is essential to maintain close communication with her healthcare team. They may want to conduct further evaluations, such as imaging studies or additional endoscopic procedures, to rule out any complications that may not have been evident during the initial assessments.

In conclusion, while post-operative vomiting can be distressing, understanding the underlying causes and implementing appropriate management strategies can significantly improve your mother's quality of life. It is crucial to work closely with her healthcare team to tailor a plan that addresses her specific needs and circumstances.

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