the Risks of Kidney Function and Lung Edema in Elderly Patients - Pulmonology

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Doctor, I apologize for asking again, but I previously inquired about my grandmother's condition, which was caused by an artificial joint leading to a bacterial infection in her internal organs.
She is currently experiencing pulmonary edema due to kidney dysfunction.
Although a urinary catheter has been inserted and diuretics are being administered, her urine output remains very low, resulting in edema in her hands.
The doctor mentioned that this is also why she is in a state of confusion.
If this continues and she does not urinate, is there a risk to her life? Is there still a chance for her to regain consciousness? Thank you!

winnie, 20~29 year old female. Ask Date: 2004/01/09

Dr. Ding Liangwen reply Pulmonology


It appears that the decrease in kidney function and subsequent reduction in urine output, along with edema and pulmonary edema, may be caused by an intra-abdominal bacterial infection triggered by the artificial joint.
If kidney function does not improve and diuretics are ineffective, dialysis may be necessary to remove excess fluid and toxins from the body.
Whether the patient will regain consciousness depends on the cause of the coma; if it is due to sepsis, there may be a chance of recovery after controlling the infection.
If it is due to severe uremia, then hemodialysis may be required.

Reply Date: 2004/01/09

More Info


Understanding the risks associated with kidney function and lung edema, particularly in elderly patients, is crucial for both caregivers and healthcare providers. In the case of your grandmother, who is experiencing lung edema due to kidney dysfunction, it is important to recognize the interplay between these two conditions and the potential implications for her health.

Lung edema, or pulmonary edema, occurs when excess fluid accumulates in the lungs, making it difficult for the patient to breathe. In elderly patients, this condition can often be linked to heart failure, kidney dysfunction, or both. The kidneys play a vital role in regulating fluid balance in the body. When kidney function declines, as indicated by low urine output and elevated creatinine levels, the body struggles to excrete excess fluid. This can lead to fluid overload, which may manifest as swelling in the hands and feet (edema) and, in more severe cases, pulmonary edema.

In your grandmother's situation, the insertion of a urinary catheter and administration of diuretics are common interventions aimed at managing fluid overload. Diuretics help the kidneys eliminate excess fluid, but their effectiveness can be limited if the kidneys are severely impaired. The fact that her urine output remains very low is concerning and suggests significant renal dysfunction. This can lead to a dangerous cycle where fluid accumulates, exacerbating lung edema and potentially leading to respiratory failure.

The risk of life-threatening complications increases when kidney function is severely compromised. If the kidneys cannot effectively filter waste products and excess fluid, this can lead to a condition known as acute kidney injury (AKI), which can be reversible but may also progress to chronic kidney disease (CKD) if not managed appropriately. In severe cases, the buildup of toxins in the bloodstream can lead to altered mental status, including confusion or coma, as seen in your grandmother's case.

As for the possibility of her waking up from this state, it largely depends on the underlying cause of her kidney dysfunction and lung edema, as well as the overall management of her condition. If the kidney damage is acute and reversible, there is a chance for recovery, especially if the underlying infection is treated effectively. However, if there is significant and irreversible damage to the kidneys, the prognosis may be less favorable.

In terms of immediate actions, it is crucial for her healthcare team to closely monitor her renal function, fluid status, and overall clinical picture. Adjustments to her medications, including diuretics and any antibiotics for the underlying infection, may be necessary. Additionally, supportive care, including oxygen therapy and possibly mechanical ventilation, may be required if her respiratory status deteriorates.

In summary, your grandmother's condition is serious, and the interplay between her kidney function and lung edema poses significant risks. Continuous monitoring and appropriate medical interventions are essential to manage her symptoms and improve her chances of recovery. It is important to maintain open communication with her healthcare team to understand her treatment plan and prognosis better.

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