HPV Results: What Does a Positive 56.66 Type Mean? - Obstetrics and Gynecology

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HPV is classified as high-risk type 56.66, and I suspect that I might have genital warts?


In the perineal area (the fold from the vaginal opening towards the anus), I felt a very small protrusion.
I went to see a gynecologist, and the doctor said it was too small to determine what it was and recommended that I get tested for HPV.
The results came back positive for HPV type 56.66, but there were no types associated with genital warts.
The doctor advised me to monitor the changes in that protrusion.
I would like to ask, if the test showed no genital wart virus, does that mean the protrusion cannot be genital warts? (I have received the nine-valent vaccine, but I started having sexual intercourse afterward.)

Aaa, 20~29 year old female. Ask Date: 2023/09/07

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, if you suspect cauliflower, a biopsy can be performed clinically.
However, a negative virus test does not necessarily mean it is not present.
Wishing you good health.

Reply Date: 2023/09/07

More Info


When you receive a positive HPV test result for types 56 and 66, it’s important to understand what this means in the context of your health. HPV, or human papillomavirus, is a group of more than 200 related viruses, some of which are classified as high-risk due to their association with certain cancers, including cervical cancer. Types 56 and 66 are considered high-risk HPV types, but they are not the most common ones associated with cervical cancer, such as types 16 and 18.

Firstly, regarding your concern about the small bump you felt in the perineal area, it’s essential to note that not all HPV infections lead to visible symptoms or lesions like genital warts (often referred to as "cauliflower" due to their appearance). Since your test results indicated that you do not have the types of HPV commonly associated with genital warts (types 6 and 11), it is less likely that the bump you are observing is a wart. However, it is still advisable to monitor the bump for any changes in size, shape, or color, and to follow up with your healthcare provider as recommended.

The fact that you have received the nine-valent HPV vaccine is a positive step. This vaccine protects against the most common high-risk HPV types, including 16 and 18, as well as low-risk types that cause genital warts. While the vaccine does not eliminate existing infections, it can help prevent new infections from the types it covers. Therefore, even if you have tested positive for types 56 and 66, the vaccine can still provide protection against other high-risk types.

In terms of treatment and management, there is currently no specific antiviral treatment for HPV itself. Most HPV infections are cleared by the immune system within two years. Regular monitoring and follow-up are crucial, especially since you have tested positive for high-risk types. Your healthcare provider may recommend routine Pap smears and HPV testing to monitor for any changes in cervical cells that could indicate precancerous changes.

It’s also important to maintain a healthy lifestyle to support your immune system. This includes a balanced diet, regular exercise, adequate sleep, and avoiding smoking and excessive alcohol consumption. These factors can enhance your body’s ability to fight off infections, including HPV.

In summary, while a positive HPV test for types 56 and 66 indicates the presence of high-risk HPV, it does not necessarily mean that you will develop health issues, especially if you are asymptomatic. The absence of genital warts in your test results is reassuring, and continued observation of the bump, along with regular check-ups, is advisable. If you notice any changes in the bump or have any concerns, do not hesitate to reach out to your healthcare provider for further evaluation. Regular screenings and maintaining a healthy lifestyle are key components in managing your health in relation to HPV.

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