Monitoring Lung Nodules and Local Fibrosis: Key Insights and Follow-Up - Pulmonology

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Follow-up on pulmonary nodules and localized fibrosis?


Dear Director, I hope you are well.
I previously consulted you on this platform on September 7, 2021, regarding my health check in October 2020, which showed pulmonary nodules and localized fibrosis on a low-dose CT scan (the case number for my last inquiry was 173071).
At that time, you suggested that I return for a follow-up low-dose CT scan in six months to a year.
I followed your advice and returned to a major hospital for a follow-up in August 2022, where the physician arranged for a standard CT scan without contrast (not low-dose, and it was one and a half years since my last inquiry on this platform).
The findings from the CT scan are as follows:
CLINICAL INFORMATION: Abnormal CT was noted, with no cough, fever, or weight loss; no active symptoms/signs of respiratory tract issues; non-smoker.
Occupation history: not specific; Allergy history: none specific; Travel history: not specific (TOCC: not specific).
Family history: no family history of asthma, allergic rhinitis, or malignancy.
STUDY OF COMPARISON: CHEST CT SCAN ON 2020-10-29 (outside hospital images).
TECHNIQUE OF EXAMINATION: Pre- and post-contrast enhanced CT scan of the chest cavity was performed.
The scanning range was from the supraclavicular region to the diaphragm.
The reconstructed thickness was 5 mm.
Soft tissue windows were displayed for evaluation.
Findings:
1.
Lower neck and supraclavicular region: Unremarkable.
2.
Lung and pleura: Focal thickening of interlobular septa and pleura over the right lower lobe (RLL) (Srs: 605 Img: 137) with no change compared to the outside hospital image study, suggesting follow-up.
3.
Mediastinum: Poor evaluation of mediastinal or hilar lymph nodes, vascular, or other conditions due to the non-contrast study, suggesting follow-up.
4.
Adrenal gland, spleen, liver, and kidney: Unremarkable.
5.
Chest wall and spine: A large nodular lesion over the right lateral abdominal wall with fat-like density, ruling out lipoma, suggesting abdominal CT evaluation.
Degenerative joint disease (DJD) of the thoracolumbar spine.
IMPRESSION: As described above.
The report indicates that compared to the low-dose CT images from one and a half years ago, the localized pleural thickening over the RLL (localized fibrosis) has not changed.
Additionally, the originally concerning 3 mm nodule (identified during the health check in October 2020 and followed up with a low-dose CT scan in February 2021, where the physician noted it was still present but had become less distinct) was not mentioned in the report of the standard chest CT performed in August 2022.
After a follow-up consultation at the hospital, the physician confirmed that the 3 mm nodule was no longer visible in this CT scan, but the fibrosis in the right upper lobe remains unchanged as stated in the report.
I would like to ask you two questions:
1.
Regarding the localized pleural thickening over the RLL noted in the August 2022 CT scan, which shows no change compared to the low-dose CT from February 2021, you previously indicated that most of the fibrous changes are unlikely to change significantly.
Given that there has been no change after one and a half years (almost two years since the initial health check), does this suggest that the fibrosis in that area is unlikely to change?
2.
The 3 mm nodule in the left lung has disappeared in the August 2022 standard CT scan compared to the low-dose CT from February 2021, and this has been confirmed by the outpatient physician.
Is it possible that the disappearance of this 3 mm nodule could be due to other reasons?
3.
Based on the CT report from August 2022, what further actions should I take?

Jerry Lin, 50~59 year old female. Ask Date: 2023/09/11

Dr. Yang Wenda reply Pulmonology


Hello: Congratulations on your recent CT report showing that the 3mm nodule has not increased in size and is no longer visible.
It is likely that it was just an inflammatory lesion that has been absorbed.
Local pleural thickening usually does not change significantly or disappear, so there is no need to worry.
It is recommended that you have a chest X-ray check-up annually!

Reply Date: 2023/09/11

More Info


Monitoring lung nodules and local fibrosis is a critical aspect of pulmonary health management, especially when previous imaging studies have indicated abnormalities. Based on your detailed history and the findings from your recent CT scans, I will address your concerns and provide insights into the implications of these findings.

1. Understanding the RLL Pleural Thickening: The report indicates focal thickening of the interlobular septa and pleura over the right lower lobe (RLL), which has remained unchanged compared to previous imaging. This suggests that the fibrosis is likely stable. In many cases, localized fibrosis, especially when it is chronic, does not progress significantly over time. The fact that there has been no change over a year and a half is reassuring. Chronic fibrotic changes can result from various causes, including previous infections, inflammation, or environmental exposures. Given that your physician has previously indicated that such changes are typically stable, it is reasonable to conclude that the localized fibrosis in your RLL is unlikely to change significantly in the future. Regular follow-up imaging, as recommended, will help ensure that any potential changes are monitored.

2. Disappearance of the 3mm Nodule: The absence of the previously noted 3mm nodule in your recent CT scan is a positive sign. Nodules can sometimes be transient and may represent benign processes such as infections, inflammation, or even artifacts from imaging. The fact that it was noted to have become less prominent in earlier scans suggests that it may have been resolving. In many cases, small nodules can disappear without intervention, particularly if they were due to a transient inflammatory process. Your healthcare provider's confirmation of its disappearance further supports the likelihood that it was not a malignant process.

3. Next Steps and Follow-Up: Given the stability of the pleural thickening and the disappearance of the nodule, your current management plan should focus on regular monitoring. It is advisable to follow your physician's recommendations regarding follow-up imaging. Typically, for stable findings like yours, follow-up CT scans may be scheduled every 6 to 12 months, depending on clinical judgment and any new symptoms that may arise. If you experience any new respiratory symptoms, such as cough, shortness of breath, or unexplained weight loss, it is crucial to inform your healthcare provider promptly, as these could warrant further investigation.

In summary, your recent imaging findings suggest stability in the areas of concern, which is encouraging. The absence of the small nodule and the unchanged status of the fibrosis indicate that there is no immediate cause for alarm. Regular follow-up with your healthcare provider will ensure that any changes in your lung health are detected early, allowing for timely intervention if necessary. Always feel free to discuss any concerns with your physician, as they can provide personalized advice based on your overall health status and history.

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