How Long Does It Take for Mifepristone to Expel Pregnancy Tissue? - Obstetrics and Gynecology

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How long does it take for Hiccup tablets to be excreted after consumption?


I am pregnant but do not wish to continue the pregnancy.
I asked the doctor to prescribe medication for a medical abortion.
The doctor instructed me to take the medication over three days.
On September 13, I took one pill of RU486.
On September 14, I took one packet of medication at 10 AM and another packet at 4 PM.
On September 15, I took the last packet of Misoprostol at 10 AM.
How soon can I expect to pass the gestational sac?

Xiao Lin, 30~39 year old female. Ask Date: 2023/09/14

Dr. Lin Manying reply Obstetrics and Gynecology


Hello: It is possible to expel after taking the first dose, please make sure to return for a follow-up appointment.
Hualien Hospital, Ministry of Health and Welfare, cares about your health.

Reply Date: 2023/09/14

More Info


Mifepristone, commonly known as RU486, is a medication used in medical abortions to terminate early pregnancies. The process typically involves taking mifepristone followed by another medication called misoprostol, which helps to expel the pregnancy tissue.
After taking mifepristone, it usually takes about 24 to 48 hours for the medication to start working. The expulsion of pregnancy tissue can occur within this timeframe, but it may take longer for some individuals. In your case, since you took mifepristone on September 13 and followed it with misoprostol on September 14 and 15, you can expect to begin experiencing symptoms such as cramping and bleeding within a few days after taking the misoprostol.
Most women will expel the pregnancy tissue within 4 to 6 hours after taking misoprostol, but it can vary. Some may experience a longer duration before the complete expulsion occurs. It is important to note that heavy bleeding and cramping are common side effects during this process, and it is essential to monitor your symptoms. If you experience excessive bleeding (soaking through two or more pads in an hour for two consecutive hours), severe pain, or any other concerning symptoms, you should seek medical attention immediately.

After the expulsion, it is advisable to have a follow-up appointment with your healthcare provider to ensure that the abortion is complete and to check for any complications. This follow-up is crucial, as retained tissue can lead to infection or prolonged bleeding.

In terms of future pregnancies, it is generally recommended to wait at least one menstrual cycle before trying to conceive again. This allows your body to recover and ensures that your menstrual cycle has returned to normal, which can help in dating a future pregnancy accurately.

Additionally, if you have any concerns about the process or your health, it is always best to consult with your healthcare provider. They can provide personalized advice based on your medical history and current health status.

In summary, after taking mifepristone and misoprostol, you can expect to expel the pregnancy tissue within a few days, typically within 4 to 6 hours after taking misoprostol. However, individual experiences may vary, and it is essential to monitor your symptoms and follow up with your healthcare provider for the best care.

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