the Effectiveness of Emergency Contraception After Ovulation - Obstetrics and Gynecology

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What is the probability of becoming pregnant if I take emergency contraception at this time?


Hello Doctor, I would like to ask a question.
The app estimated the ovulation date to be September 12.
On September 14, I had unprotected intercourse with my girlfriend (without ejaculation), but I was concerned about the sperm in the pre-ejaculate fluid.
Therefore, on September 15, about 40 hours after the incident, my girlfriend took a second-generation emergency contraceptive pill (Ella).
After taking it, she did not experience withdrawal bleeding, only some soreness and abdominal discomfort as side effects.
I would like to ask the doctor, what is the likelihood of pregnancy in this situation? Additionally, I have seen many people online saying that taking emergency contraception after ovulation is ineffective, while others claim that second-generation emergency contraceptives can inhibit implantation after ovulation.
Could you please clarify the function of second-generation emergency contraceptives and the effectiveness of taking them after ovulation? My girlfriend is very anxious every day, so I wanted to inquire quickly.
We will also take proper precautions in the future.
Thank you, Doctor, for your hard work.

Chen, 20~29 year old female. Ask Date: 2023/09/19

Dr. Zhang Kunmin reply Obstetrics and Gynecology


Hello, the questioner: There is a possibility of pregnancy even if ejaculation has not occurred during intercourse, as pre-ejaculatory fluid may contain sperm.
Additionally, the effectiveness of emergency contraception is not 100%, with a failure rate of about 3%, but it is still considered a remedial option.
It is recommended to check for pregnancy if menstruation is more than a week late.
The second-generation oral emergency contraceptive pill primarily contains Ulipristal acetate, which is a synthetic selective progesterone receptor modulator that binds very effectively to the human progesterone receptor.
In contrast, the older component, Levonorgestrel, uses a high dose of progesterone to inhibit or delay ovulation.
Studies have indicated that the newer generation of contraceptives is more effective than the older ones, remaining effective even when taken within 5 days after intercourse, although it is still advisable to take it as soon as possible.
Thank you! Wishing you peace and health.
Dr.
Zhang

Reply Date: 2023/09/19

More Info


When it comes to understanding the effectiveness of emergency contraception (EC) after ovulation, it's important to clarify how these medications work and their timing in relation to the menstrual cycle. In your case, you mentioned that ovulation was estimated to occur on September 12, and unprotected intercourse happened on September 14. You took the emergency contraceptive pill (Ella) approximately 40 hours later, on September 15.

Ella, which contains ulipristal acetate, is a second-generation emergency contraceptive that is effective in preventing pregnancy primarily by delaying or inhibiting ovulation. It is most effective when taken before ovulation, but it can still be effective after ovulation, particularly if taken within a few days of the event. However, its effectiveness diminishes as time passes after ovulation.
Regarding your concerns about the likelihood of pregnancy, it is essential to understand that while Ella can inhibit ovulation, if ovulation has already occurred and the egg has been released, the primary mechanism of action may not be effective. There is some evidence suggesting that Ella may alter the endometrial lining, potentially preventing implantation of a fertilized egg, but this is not its primary function and is less understood.
The absence of withdrawal bleeding after taking Ella does not necessarily indicate that the medication was ineffective. Side effects such as abdominal pain or discomfort can occur and are not uncommon. It's also important to note that the timing of taking the pill in relation to ovulation is crucial. If ovulation has already occurred, the chances of preventing pregnancy decrease, but it does not mean that pregnancy is guaranteed.

In terms of the effectiveness of emergency contraception after ovulation, studies have shown that while Ella can still be effective, its efficacy is significantly higher when taken before ovulation. The consensus in the medical community is that while there is a possibility of preventing pregnancy even after ovulation, the chances are lower compared to taking it before ovulation.

In summary, while the risk of pregnancy exists after taking Ella post-ovulation, it is not a certainty. If your girlfriend experiences any unusual symptoms or if her period is significantly delayed, it would be advisable for her to take a pregnancy test or consult a healthcare provider for further evaluation.
For future reference, using regular contraception methods, such as condoms or hormonal birth control, can significantly reduce the anxiety surrounding unprotected intercourse. Emergency contraception should be viewed as a backup method rather than a primary form of birth control. It's great to hear that you plan to take safety measures in the future, as this will help alleviate concerns and ensure both partners feel secure in their sexual health practices.

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