Instrument examination
Several years ago, a family member underwent surgery for liver cancer and had a good recovery, with follow-ups every three months.
Recently, a CT scan indicated a gray shadow on the liver, prompting the doctor to schedule blood tests and a nuclear magnetic resonance (NMR) examination.
The blood tests showed all liver parameters within normal ranges, but the NMR report included the following findings:
MR of the Liver, Structural Report:
- Cor FIESTA +FS, Large FOV
- Axi Dynamic LAVA 3D, 0, 30s, 1, 3, and 5 mins, 5-mm slice.
Indication(s): HCC + CCC S/P OP.
FU Comparison: CT on 2023-06-08, 2022-04-19.
Findings:
1.
Tumor profiles:
- Prior management: partial hepatectomy of segments S5/S6, S4/S5/S8.
- Local recurrence (viable):
- A growing nodule with early enhancement and early washout at the S2/S3 junction, approximately 2 cm in size, favoring HCC.
- About three poorly enhanced nodules at S2, S6, and S7, ranging from 0.5 to 1.3 cm in size, relatively stable or slightly larger than previous studies, suspected to be regenerative nodules or hypovascular HCCs, suggesting close follow-up.
2.
Interval change: The S2/S3 lesion is larger than in prior studies.
3.
Portal vein: Patent.
4.
Regional lymphadenopathy: None.
5.
Cirrhosis of the liver: None.
6.
Ascites: None.
7.
Splenomegaly: None.
8.
Portosystemic collaterals: None.
9.
Biliary tree: Unremarkable.
10.
Pancreas: Unremarkable.
11.
Kidneys: Unremarkable.
12.
Adrenals: Unremarkable.
Impression: A growing HCC at the S2/S3 junction, 2 cm, and several stable washout nodules at S2, S6, and S7.
Based on the above examination, is the recurrence confirmed as local recurrence (viable)? What is the difference between nuclear magnetic resonance and computed tomography? Does the impression indicate a definitive diagnosis of liver cancer?
Jj, 30~39 year old female. Ask Date: 2023/09/21
Dr. Chen Sirong reply Oncology
Jj / 31 years old / Male
1.
Is the recurrence confirmed as a local recurrence (viable)?
A:
2.
Local recurrence (viable): - A growing nodule with early enhancement and early washout at the S2/S3 junction, approximately 2 cm in size, suggestive of hepatocellular carcinoma (HCC).
What is the difference between nuclear magnetic resonance and computed tomography?
A: Primarily specialized liver magnetic resonance imaging.
3.
Does the preliminary diagnosis imply a confirmed diagnosis of liver cancer?
A: You keep saying confirmed; in terms of imaging, it can be considered confirmed, but a biopsy or resection is necessary for definitive confirmation.
Wishing you a smooth treatment, Taoyuan Hospital, Chen Si-Rong.
Reply Date: 2023/09/21
More Info
Understanding the differences between MRI and CT scans, especially in the context of liver cancer follow-up care, is crucial for managing patient health effectively. In your case, the MRI report indicates a growing nodule at the S2/S3 junction, which is concerning for hepatocellular carcinoma (HCC) recurrence. This finding is significant, particularly given your family history of liver cancer and the previous surgical intervention.
MRI vs. CT Scans
1. Imaging Techniques:
- CT Scans (Computed Tomography): CT uses X-rays to create detailed images of the body. It is particularly useful for quickly assessing the size and shape of tumors and can provide information about the surrounding structures. However, it does involve exposure to ionizing radiation, which, while generally considered safe, can accumulate over time and potentially increase cancer risk.
- MRI (Magnetic Resonance Imaging): MRI uses magnetic fields and radio waves to produce detailed images of organs and tissues. It does not involve radiation, making it a safer option for repeated imaging. MRI is particularly effective in differentiating between various types of soft tissue, which is beneficial in characterizing liver lesions.
2. Specificity and Sensitivity:
- MRI is often more sensitive than CT for detecting liver lesions, especially small ones. It can provide better contrast resolution, which is essential for distinguishing between benign and malignant lesions. In your case, the MRI findings suggest a viable tumor with characteristics typical of HCC, which raises the suspicion of recurrence.
- CT scans are generally faster and may be preferred in emergency situations or when rapid assessment is needed. However, for follow-up in liver cancer, MRI is often favored due to its superior detail in soft tissue imaging.
Interpretation of MRI Findings
The MRI report indicates a growing nodule at the S2/S3 junction, approximately 2 cm in size, which is concerning for HCC recurrence. The report also mentions several other nodules that are stable or slightly larger, which may represent regenerative nodules or hypovascular HCCs. The term "local recurrence (viable)" suggests that there is a high likelihood that the growing nodule is indeed cancerous, but definitive diagnosis often requires a biopsy for histological confirmation.
Follow-Up and Monitoring
Given the findings, it is crucial to discuss the next steps with your healthcare provider. Regular follow-up is essential in the management of liver cancer, especially after surgical intervention. The frequency of imaging studies can vary based on individual risk factors and the specific characteristics of the lesions.
- Frequency of Imaging: Typically, after treatment for liver cancer, patients may undergo imaging every 3 to 6 months for the first few years. If the lesions are stable and there are no signs of recurrence, the frequency may be reduced.
- Choice of Imaging Modality: While MRI is excellent for soft tissue evaluation, CT scans may still be used in certain situations. The decision on which imaging modality to use should be based on clinical judgment, patient history, and the specific characteristics of the lesions.
Conclusion
In summary, the MRI findings suggest a high likelihood of HCC recurrence at the S2/S3 junction, and it is essential to have a thorough discussion with your healthcare provider regarding the implications of these findings and the best course of action. Regular monitoring through appropriate imaging modalities is crucial for early detection of any recurrence or new lesions. Always ensure that your follow-up care is tailored to your specific medical history and current health status.
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