Abnormal Urinalysis Results: CREA and Color Insights - Internal Medicine

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Urinalysis report


CREA(U) (semi-quantitative) 100 mg/dL (-) pH 7.5 Bilirubin negative Color Straw (yellow) Glucose negative Ketone negative MALB(U) (semi-quantitative) 10 mg/L (0-29) Nitrite negative Protein negative SP.Gravity 1.009 (1.003-1.035) Turbidity Clear UACR(U) semi-quantitative Normal (<30 mg/g) Urobilinogen Normal (<2) WBC esterase negative Blood negative
This is a urine test conducted in the hospital, which showed CREA(U) at 100 mg/dL, with the standard being negative.
Additionally, the color is noted as straw, while the standard is yellow.
I had consumed a considerable amount of water prior to the test.
I would like to know what these two abnormalities indicate and whether they are serious.

Guang, 40~49 year old female. Ask Date: 2023/10/03

Dr. Gao Jiankai reply Internal Medicine


Hello, thank you for your question.
The difference between yellow and straw-colored urine is minimal, and if there are no other abnormalities in the urine test, I believe it is not a concern.
As for urine creatinine, it is related to kidney function, but in young males who consume excessive amounts of meat or engage in intense exercise, the levels may also rise.
This should be evaluated in conjunction with other test results.
Since your other test results are normal, I still think a slight increase in urine creatinine is not a concern.
If you have any doubts, I recommend consulting a nephrologist.
The Allergy, Immunology, and Rheumatology Department of Changhua Hospital, Ministry of Health and Welfare, cares about you.

Reply Date: 2023/10/03

More Info


Understanding abnormal urinalysis results can be crucial for diagnosing potential health issues. In your case, the results show a CREA (creatinine) level of 100 mg/dL, which is flagged as abnormal, and the urine color is noted as straw instead of the standard yellow. Let's break down what these findings might indicate.


CREA (Creatinine) Level
Creatinine is a waste product generated from muscle metabolism and is typically filtered out of the blood by the kidneys. The normal range for creatinine in urine can vary, but a level of 100 mg/dL is considered elevated. This could indicate several things:
1. Dehydration: Since you mentioned that you drank a lot of water before the test, it’s possible that the creatinine level is elevated due to a temporary fluctuation. However, if you were dehydrated prior to drinking water, it could also lead to a higher concentration of creatinine.

2. Kidney Function: Elevated creatinine levels can indicate impaired kidney function. If the kidneys are not filtering waste effectively, creatinine levels in the urine can rise. This could be due to various conditions, including chronic kidney disease, acute kidney injury, or other renal pathologies.

3. Muscle Mass: Individuals with higher muscle mass may naturally have higher creatinine levels. If you are physically active or have a muscular build, this could be a contributing factor.


Urine Color
The color of urine can provide insights into hydration status and potential health issues. Normal urine color ranges from pale yellow to deep amber, primarily due to the pigment urochrome.
- Straw Color: A straw color indicates a more diluted urine, which is generally a sign of good hydration. However, if your urine is consistently straw-colored and you are experiencing other symptoms, it may warrant further investigation.


Clinical Significance
While the elevated CREA level is concerning, it is essential to interpret these results in the context of your overall health, symptoms, and medical history. Here are some steps you might consider:
1. Follow-Up Testing: It would be prudent to repeat the urinalysis after a period of normal hydration and possibly conduct additional tests, such as serum creatinine levels, to assess kidney function more accurately.

2. Hydration Status: Ensure that you maintain adequate hydration, as both dehydration and overhydration can affect urine concentration and composition.

3. Consult a Healthcare Provider: Discuss these results with your healthcare provider, who may recommend further evaluation based on your medical history, symptoms, and any other relevant tests.

4. Monitor Symptoms: Pay attention to any symptoms such as changes in urination frequency, pain during urination, swelling, or fatigue, which could indicate underlying issues that need to be addressed.


Conclusion
In summary, while an elevated CREA level and a straw-colored urine sample can raise concerns about kidney function and hydration status, they are not definitive indicators of a serious condition on their own. It is essential to consider these results in conjunction with your overall health and to consult with a healthcare professional for a comprehensive evaluation and appropriate management. Regular monitoring and follow-up tests can help clarify the situation and guide any necessary interventions.

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