Optic Nerve Cupping and Glaucoma in High Myopia - Ophthalmology

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Optic cup excavation and glaucoma?


I'm sorry, doctor.
I have high myopia (approximately over -600 diopters in both eyes) and high astigmatism (approximately over -500 diopters in both eyes).
Today, I went to a major hospital for an eye examination, and the doctor said that my retina looks fine, but the optic cup-to-disc ratio is quite severe.
The OCT scan indicated that the upper part of the optic nerve is thinning, and the doctor mentioned that a visual field test is necessary, although my intraocular pressure is normal.
Many years ago, I had a visual field test, and the doctor noted some slight defects in the lower visual field, but my mother said the doctor did not prescribe any eye drops for me.
When I was younger, I also heard the doctor mention that some people are born with a naturally narrower optic nerve and visual field, suggesting that it might be congenital.
Today's doctor also mentioned that it could be a congenital condition.

1.
If it is congenital optic nerve atrophy and a narrower visual field, does that mean it will not worsen?
2.
If a follow-up visual field test reveals actual defects, along with the OCT showing optic nerve thinning, would that lead to a direct diagnosis of glaucoma?
3.
Given that my intraocular pressure is normal, does that mean it is a case of "normal-tension glaucoma"? If I already have low intraocular pressure, would treatment aimed at lowering eye pressure be ineffective? I'm very concerned that low-tension glaucoma might be more difficult to manage than high-tension glaucoma!

Niming, 20~29 year old female. Ask Date: 2023/10/03

Dr. Liang Ce reply Ophthalmology


Recommendations: 1.
Discuss the above situation further with your attending physician.
2.
Alternatively, seek consultation at another ophthalmology medical facility.
Thank you.
Wishing you good health!

Reply Date: 2023/10/03

More Info


Understanding optic nerve cupping and its relationship with glaucoma, especially in the context of high myopia, is crucial for maintaining eye health. As a person with high myopia (around -600 degrees) and significant astigmatism, you are at a higher risk for various ocular conditions, including glaucoma. Here’s a detailed response to your questions:
1. Congenital Optic Nerve Atrophy and Narrow Visual Field: If your optic nerve cupping and narrow visual field are congenital (i.e., you were born with these characteristics), it does not necessarily mean that your condition will worsen. Some individuals have anatomical variations that do not progress to disease. However, it is essential to monitor these changes over time. Regular follow-ups with your ophthalmologist are crucial to assess any changes in your optic nerve and visual field.

2. Diagnosis of Glaucoma: If future visual field tests reveal defects alongside thinning of the optic nerve as seen on OCT (Optical Coherence Tomography), it could indicate the presence of glaucoma. However, a definitive diagnosis requires a comprehensive evaluation, including intraocular pressure (IOP) measurements, visual field testing, and assessment of the optic nerve head. Glaucoma can be classified into different types, and the presence of optic nerve cupping and visual field loss is significant in diagnosing the condition.

3. Normal Intraocular Pressure and Low-Pressure Glaucoma: Having normal intraocular pressure does not exclude the possibility of glaucoma. There is a subtype known as normal-tension glaucoma (NTG) or low-pressure glaucoma, where optic nerve damage occurs despite IOP being within the normal range (typically 10-21 mmHg). If you are diagnosed with NTG, lowering the IOP may not be as effective as in high-pressure glaucoma. Therefore, treatment strategies may focus on neuroprotection and monitoring rather than solely on lowering pressure.

4. Concerns About Low-Pressure Glaucoma: Your concern about low-pressure glaucoma being more challenging to manage is valid. While it may be more difficult to treat, it is essential to work closely with your ophthalmologist to develop a tailored management plan. This may include regular monitoring, lifestyle modifications, and possibly medications or surgical interventions if necessary.

5. Monitoring and Follow-Up: Given your history of visual field loss and the current findings of optic nerve cupping, it is vital to have regular follow-ups. Your ophthalmologist may recommend periodic visual field tests and OCT scans to monitor any changes in your optic nerve and visual field. Early detection and intervention are key in managing glaucoma effectively.

6. Lifestyle Considerations: Maintaining a healthy lifestyle can contribute to overall eye health. This includes regular exercise, a balanced diet rich in antioxidants (like leafy greens and fish), and avoiding smoking. Additionally, managing systemic health conditions (like hypertension or diabetes) is crucial as they can impact ocular health.

In conclusion, while your current findings raise some concerns, it is essential to approach this situation with careful monitoring and regular consultations with your eye care provider. Understanding the nuances of your condition will empower you to take proactive steps in managing your eye health effectively. Always feel free to ask your ophthalmologist any questions you may have during your visits, as they can provide personalized insights based on your specific situation.

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