Managing Chronic Urticaria: Medication, Allergies, and Health Concerns - Internal Medicine

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Chronic urticaria


Hello, doctor.
I would like to ask if chronic urticaria can only be managed with medication.
I have been taking antihistamines for over two months, and during that time, I felt fine without itching, although sometimes my skin would be a bit red.
A few years ago, I had allergy testing done, which showed that I am allergic to dust mites.
However, when I visited a dermatology clinic, they drew blood, and the report only indicated a positive antinuclear antibody (ANA) at a titer of 1:80.
Now, I am unsure whether I should return to that clinic or switch to another one.
They suggested that I go to Chang Gung Memorial Hospital for another blood test, but I find it cumbersome and don't have the time to keep going to large hospitals.
I feel stuck and don't know what to do.
Additionally, I would like to ask if urticaria can be related to HIV.
However, I have not had sexual intercourse for over a year, and I have tested negative for HIV three times during this period, as well as for syphilis.
I apologize for the lengthy message, and thank you, doctor.

Xiao Zhe, 30~39 year old female. Ask Date: 2023/10/13

Dr. Gao Jiankai reply Internal Medicine


Hello, thank you for your question.
The result of the antinuclear antibody (ANA) test is acceptable; although it is marked as positive, the value is still within an acceptable range according to rheumatology standards, so there is no need to worry too much.
Regarding chronic urticaria, there are several factors to consider.
In addition to allergies, it may also be related to immune dysfunction, infections, and endocrine disorders.
Therefore, some physicians may test for HIV and syphilis.
I recommend consulting a nearby rheumatologist, clearly explaining your condition, and asking them to conduct a detailed examination.
The Allergy, Immunology, and Rheumatology Department at Changhua Hospital of the Ministry of Health and Welfare is here to support you.

Reply Date: 2023/10/13

More Info


Chronic urticaria, commonly known as chronic hives, is a condition characterized by the recurrent appearance of itchy welts or hives on the skin. Managing this condition can be challenging, and it often requires a multifaceted approach. Let's address your concerns regarding medication, allergies, and health issues related to chronic urticaria.


Medication Management
You mentioned that you have been taking antihistamines for over two months, which is a common first-line treatment for chronic urticaria. Antihistamines work by blocking the action of histamine, a substance in the body that causes allergic symptoms. It's not uncommon for patients to experience relief from itching and redness while on these medications. However, chronic urticaria can be a persistent condition, and some individuals may need to continue medication for an extended period, sometimes even indefinitely, to manage their symptoms effectively.

If you find that antihistamines are effective but you are concerned about long-term use, it is worth discussing this with your healthcare provider. They may consider alternative treatments, such as:
1. Higher Doses of Antihistamines: Some patients benefit from taking higher doses than typically recommended.

2. Other Medications: In cases where antihistamines are insufficient, medications such as corticosteroids, leukotriene receptor antagonists, or even newer biologic therapies like omalizumab (Xolair) may be considered.

3. Immunosuppressants: In severe cases, medications that suppress the immune system may be necessary.


Allergy Testing and Management
You mentioned a previous allergy test that indicated sensitivity to dust mites. This is a common allergen and can contribute to allergic reactions, including urticaria. If you suspect that your chronic urticaria is related to environmental allergens, it may be beneficial to take steps to minimize exposure to these allergens. This can include:
- Using dust mite-proof covers on pillows and mattresses.

- Regularly washing bedding in hot water.

- Keeping humidity levels low in your home.

- Vacuuming frequently with a HEPA filter vacuum.

Regarding the positive antinuclear antibody (ANA) test, this can indicate an autoimmune process, but it does not necessarily correlate with your urticaria. It may be prudent to follow up with a rheumatologist or your primary care physician to interpret this result in the context of your overall health.


Follow-Up Care
You expressed uncertainty about whether to return to your previous dermatologist or seek a new one. If you feel that your current care is not meeting your needs or if you are uncomfortable with the recommendations, it is entirely reasonable to seek a second opinion. A fresh perspective may provide new insights or treatment options that could be beneficial.


Concerns About HIV
You also inquired about the relationship between chronic urticaria and HIV. While chronic urticaria is not directly linked to HIV, certain infections can trigger or exacerbate urticaria in some individuals. Given your history of sexual activity and your concerns, it is understandable to want reassurance regarding your HIV status. Since you have tested negative multiple times over the past year, it is unlikely that HIV is the cause of your urticaria. However, if you have ongoing concerns, discussing them with a healthcare provider may help alleviate your anxiety.


Conclusion
In summary, managing chronic urticaria often requires ongoing medication, lifestyle modifications to reduce allergen exposure, and regular follow-up with healthcare providers. If you are experiencing difficulties with your current treatment plan or have concerns about your health, do not hesitate to seek further evaluation or a second opinion. Your health and comfort are paramount, and finding the right approach to manage your condition is essential.

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