Brain Tumors: Surgery Success Rates and Risks - Neurosurgery

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Brain tumor


Dear Doctor,
My father is 53 years old and has been diagnosed with a brain tumor for nearly a year.
Since the diagnosis, the tumor has not grown, but the cerebral edema has worsened.
His symptoms primarily include headaches, pulsatile tinnitus, tinnitus, unsteady gait, memory decline, and weakness in his left leg.
The tumor is located in the right frontal lobe, and the doctor has identified it as a meningioma, measuring 4x3x3 cm.
However, my father strongly opposed surgery initially, so a biopsy has never been performed, and it remains unknown whether it is benign or malignant.
The cerebral edema is severe, and MRI scans show almost no space on the left side.
Additionally, he has arrhythmia with bradycardia and has a pacemaker implanted.
I would like to ask you a few questions: What is the general success rate of brain tumor surgery currently? Is it possible to perform surgery to remove the tumor in the presence of severe cerebral edema? Generally speaking, what is the likelihood of postoperative complications? What are the potential complications? Given my father's condition, what is the probability of a successful surgery?
I apologize for taking up your time, and I greatly appreciate your response.
Wishing you a Happy New Year.

eliza, 20~29 year old female. Ask Date: 2004/01/18

Dr. Shao Guoning reply Neurosurgery


Hello: In response to your question, meningiomas are, in very rare cases, benign tumors.
In other words, they do not metastasize, and as long as they are completely surgically removed, they will not recur.
Although meningiomas grow slowly, the brain is encased in the skull, leaving limited space for tumor growth.
Additionally, the mass effect of the tumor can cause various neurological symptoms or invade nearby vascular and nerve structures, making surgical removal necessary after careful clinical evaluation.
According to your letter, your father's meningioma is located in the right frontal lobe, measuring approximately 4x3x3 cm, and has already caused some neurological symptoms and obstructive hydrocephalus, which requires surgical intervention.
This can be managed in medium to large hospitals, with minimal or no residual effects.
Postoperative complications can range from severe outcomes like death to milder issues such as altered consciousness, personality changes, facial expression and speech impairments, motor deficits or paralysis, bleeding, seizures, and hydrocephalus, among others.
Even though your father has arrhythmia and is equipped with a pacemaker, overall, he is still young and should not easily give up on treatment opportunities.

Reply Date: 2004/01/18

More Info


When considering brain tumor surgery, particularly for a meningioma located in the frontal lobe, there are several factors to evaluate regarding the risks, success rates, and potential outcomes. Your father's situation, characterized by significant symptoms such as headaches, tinnitus, unsteady gait, memory decline, and left leg weakness, indicates that the tumor is likely affecting nearby brain structures. The presence of severe edema (swelling) further complicates the clinical picture and may necessitate surgical intervention.


Success Rates of Brain Tumor Surgery
The success rate of brain tumor surgeries can vary widely based on several factors, including the type of tumor, its location, the patient's overall health, and the surgical technique used. Meningiomas, which are typically benign, have a generally favorable prognosis when surgically removed. The success rate for complete resection of a meningioma can be as high as 90% in some cases, especially if the tumor is well-defined and not infiltrating surrounding brain tissue. However, in cases where the tumor is larger or located near critical brain structures, the success rate may decrease.


Surgical Considerations with Severe Edema
In cases of severe edema, surgery can still be performed, but it may carry additional risks. The presence of significant swelling can make it more challenging to visualize the tumor and surrounding structures during surgery, potentially leading to complications. Surgeons often take a cautious approach, and in some cases, they may opt for a preoperative treatment to reduce edema before proceeding with surgery. This could involve corticosteroids or other medications to manage swelling.


Risks and Potential Complications
Every surgical procedure carries risks, and brain surgery is no exception. Common risks associated with brain tumor surgery include:
1. Neurological Deficits: Depending on the tumor's location, patients may experience changes in speech, motor function, or sensory perception. These deficits can range from mild to severe.


2. Seizures: Postoperative seizures are a potential complication, particularly if the tumor was located in an area of the brain that is responsible for electrical activity.

3. Infection: As with any surgical procedure, there is a risk of infection at the surgical site.

4. Cerebrospinal Fluid (CSF) Leak: This can occur if the protective layers around the brain are disrupted during surgery.

5. Edema: Postoperative swelling can occur, which may require further treatment.

6. Mortality: While rare, there is a risk of death associated with brain surgery, particularly in patients with significant comorbidities.


Postoperative Outcomes
The likelihood of postoperative complications and the overall success of the surgery depend on various factors, including the patient's age, pre-existing health conditions (such as the heart rhythm issues your father has), and the tumor's characteristics. Given your father's age and existing health concerns, these factors must be carefully weighed against the potential benefits of surgery.


Conclusion
In summary, while the surgery for a meningioma can be successful with a high rate of tumor removal, the presence of severe edema and other health issues complicates the situation. It is crucial for your father to have a thorough discussion with his neurosurgeon about the risks and benefits of surgery, considering his specific health profile. The surgical team can provide a tailored assessment based on imaging studies, the tumor's characteristics, and your father's overall health status.
Ultimately, the decision to proceed with surgery should be made collaboratively, taking into account the potential for improved quality of life against the risks involved. It is also essential to explore all available treatment options, including medical management of symptoms, to ensure a comprehensive approach to your father's care.

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