Managing Ear Infections: Duration of Antibiotic Treatment Explained - Otolaryngology

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Duration of antibiotic therapy?


I have been experiencing fluid discharge from my ear, along with purulent secretion and a black mold infection.
I have been treated with antibiotics and ear drops for a long time without improvement.
Eventually, the doctor I consulted said that my eardrum is inflamed and appears abnormal.
A bacterial culture identified Staphylococcus aureus.
I switched to using ear drops that contain a different formulation, and I feel some improvement; the feeling of fullness has disappeared.
However, I have been using them for over 14 days, and the doctor mentioned that the eardrum still feels moist, so I should continue using the drops.
Yet, I noticed on the prescription that it states not to exceed 10 days.
Should I continue using the drops? I would appreciate Dr.
Cheng's guidance on this matter.
Thank you.

Francine, 60~69 year old female. Ask Date: 2023/10/22

Dr. Zheng Jueyi reply Otolaryngology


If the clinician recommends it, you may use the ear drops for another week and return for a follow-up evaluation to assess whether there has been improvement.

Reply Date: 2023/10/22

More Info


Managing ear infections, particularly those involving the outer ear (otitis externa) and middle ear (otitis media), can be complex, especially when there are complications such as fungal infections or bacterial superinfections. Your situation, involving persistent symptoms despite treatment, raises several important considerations regarding the duration of antibiotic therapy and the management of ear infections.

Firstly, it is essential to understand that the duration of antibiotic treatment can vary significantly based on the type and severity of the infection, the specific pathogens involved, and the patient's overall health. In cases of bacterial otitis media, for instance, the standard treatment duration is typically around 10 to 14 days, depending on the age of the patient and the severity of the symptoms. However, in cases where there is a more complicated infection, such as one involving resistant bacteria like Staphylococcus aureus (which you mentioned as being identified in your culture), a longer duration of treatment may be necessary.

In your case, you have been using ear drops for over 14 days, and while you have noted some improvement, the physician has indicated that your eardrum still appears moist. This is a critical observation because a persistently moist eardrum can indicate ongoing inflammation or infection, which may require further intervention. The fact that you were initially treated with different medications that did not yield improvement suggests that the infection may be more resistant or complicated than initially thought.

Regarding the use of the ear drops (耳朵贊耳滴劑), it is crucial to follow your physician's guidance. If the medication instructions indicate not to exceed 10 days, it is generally advisable to adhere to this guideline unless your doctor has specifically directed you to continue beyond that timeframe due to your unique circumstances. Prolonged use of topical antibiotics can lead to issues such as local irritation or the development of antibiotic resistance, which could complicate future treatment options.

If you are experiencing significant improvement, such as the resolution of the feeling of fullness in your ear, this is a positive sign. However, if you still have concerns about the moisture in your eardrum or if symptoms such as pain, discharge, or hearing loss persist, it would be prudent to follow up with your healthcare provider. They may consider alternative treatments, such as a different class of antibiotics, antifungal medications if a fungal infection is suspected, or even a referral to an ear, nose, and throat (ENT) specialist for further evaluation.

In summary, while the duration of antibiotic treatment can vary, it is essential to follow your physician's recommendations closely. If you have concerns about the effectiveness of your current treatment or the instructions regarding the duration of use, do not hesitate to reach out to your healthcare provider for clarification. They can provide personalized advice based on your specific situation and ensure that you receive the most appropriate care for your ear infection.

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