Unusual Bleeding After Medication: Why Is It Increasing? - Obstetrics and Gynecology

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Abnormal bleeding, with increased blood volume after taking medication?


I had my menstrual period from October 26 to October 31.
Then, on November 5, I experienced unexpected bleeding, but the amount was not significant—just enough to require a panty liner.
The doctor examined me and said there were no issues with my cervix, so I just needed to adjust my hormones.
I started taking medication from October 6 and continued until the evening of October 7, but the bleeding has been increasing.
I am becoming very worried about whether there is a problem, especially since the amount has not decreased and has even increased, along with blood clots.
The doctor prescribed me the following medications: 1.
CLOMIPHENE CAPSULES, 2.
ZEDIOL F.C., 3.
TRANEXAMIC ACID CAPSULES.
Should I continue taking the medication since the effects may not have reached their peak yet, and I shouldn't be anxious (the doctor prescribed it for five days, and I have currently taken it for two days)?

Kk, 40~49 year old female. Ask Date: 2023/11/08

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, it is recommended to return to the original clinic for treatment.
Wishing you good health.

Reply Date: 2023/11/08

More Info


Unusual bleeding can be a concerning issue, especially when it occurs outside of the normal menstrual cycle. In your case, it seems that you experienced a sudden onset of bleeding after your menstrual period, which has increased in volume despite being on medication. This situation can understandably lead to anxiety and worry about underlying health issues.

From your description, it appears that you have been prescribed Clomiphene, Zediol (which contains estrogen), and Tranexamic acid. Clomiphene is often used to induce ovulation, particularly in women who may have irregular cycles or difficulty conceiving. Zediol, being a form of estrogen, can help regulate hormonal imbalances, while Tranexamic acid is typically used to reduce excessive bleeding by helping the blood clot more effectively.

The increase in bleeding you are experiencing could be attributed to several factors:
1. Hormonal Fluctuations: When starting hormonal medications, it is not uncommon for the body to take some time to adjust. Clomiphene, in particular, can lead to fluctuations in hormone levels, which might cause irregular bleeding or spotting as your body responds to the medication. It may take a few cycles for your body to stabilize.

2. Medication Timing: Since you mentioned that you started taking the medications on October 6 and are currently on day 2 of a five-day course, it is possible that the full effects of the medications have not yet been realized. Hormonal medications often require time to exert their effects, and it may take several days or even weeks for you to notice a significant change in your bleeding pattern.

3. Underlying Conditions: While your doctor has indicated that there are no issues with your cervix, it is still important to consider other potential causes of abnormal bleeding, such as uterine fibroids, polyps, or endometrial issues. If the bleeding continues to increase or if you experience severe pain, it would be prudent to follow up with your healthcare provider for further evaluation.

4. Stress and Lifestyle Factors: Stress, fatigue, and lifestyle changes can also impact your menstrual cycle and bleeding patterns. If you are experiencing significant stress or changes in your routine, this could contribute to hormonal imbalances that manifest as unusual bleeding.

Given that you are only two days into your medication regimen, it is advisable to continue taking the medications as prescribed and monitor your symptoms. If the bleeding does not decrease or worsens, or if you experience any additional concerning symptoms (such as severe pain, dizziness, or large blood clots), you should contact your healthcare provider promptly for further assessment.

In summary, while it is natural to feel anxious about unusual bleeding, it is essential to give your body some time to adjust to the medications. Keep track of your symptoms, and do not hesitate to reach out to your healthcare provider if you have any concerns. They can provide guidance and may consider further investigations if necessary to ensure your health and well-being.

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