Hepatitis B: Infection History, Antibodies, and Breastfeeding Concerns - Gastroenterology and Hepatology

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Hepatitis B Infectivity Issues


Hello Doctor, I have the following results from my prenatal check-ups: HBsAg (Hepatitis B surface antigen) is negative, HBeAg (Hepatitis B e antigen) is negative.
In March of this year, the results showed HBsAg negative, anti-HBs (Hepatitis B surface antibody) positive, anti-HBc (Hepatitis B core antibody) positive, and HBeAg negative.
In August, the HBsAg remained negative.
I have the following questions:
1.
Does this mean I have had a past Hepatitis B infection? If there is a possibility of infection, can I get infected again?
2.
Will these antibodies disappear, or will they remain for life?
3.
Do I need to receive the Hepatitis B vaccine in this situation?
4.
I am currently breastfeeding; is there a risk of transmission to my child? Do I need to undergo any specific tests?
5.
Do I need regular follow-up? If so, what tests should I undergo?
Thank you very much for your response, Doctor.

Doreen, 30~39 year old female. Ask Date: 2023/11/08

Dr. Chen Shidian reply Gastroenterology and Hepatology


Having antibodies indicates immunity, and as a member of the general public, there is no need for concern.

Reply Date: 2023/11/08

More Info


Hello! Thank you for your questions regarding Hepatitis B, and I’m glad to provide some clarity on this important topic.

1. Have I had Hepatitis B?
Based on your test results, it appears that you have been exposed to the Hepatitis B virus (HBV) in the past. The presence of Hepatitis B surface antibodies (Anti-HBs) and core antibodies (Anti-HBc) indicates that you have either cleared a past infection or have been vaccinated. Since both your Hepatitis B surface antigen (HBsAg) and E antigen (HBeAg) are negative, it suggests that you are not currently infected with the virus. However, it is important to note that while you may have had an infection in the past, the risk of reinfection is low if you have developed immunity.

2. Will these antibodies disappear?
Hepatitis B antibodies can persist for many years, often for life, especially if you have cleared the infection. However, in some cases, antibody levels may decline over time. Regular monitoring of your antibody levels can help determine if they remain protective.

3. Do I need the Hepatitis B vaccine?
Since you have positive antibodies, you likely do not need the Hepatitis B vaccine, as you are already immune. Vaccination is typically recommended for individuals who are at risk of infection and do not have immunity.

4. Breastfeeding and transmission risk:
You can safely breastfeed your child. The Hepatitis B virus is not transmitted through breast milk. However, if you have any open wounds or bleeding, it is advisable to take precautions to avoid direct contact with your child’s skin. There is no need for additional testing for your child unless there are specific concerns or symptoms.

5. Do I need regular follow-ups?
Regular follow-ups are generally recommended for individuals with a history of Hepatitis B, especially if there are any changes in your health or if you have risk factors for liver disease. Follow-up tests may include liver function tests, HBV DNA tests, and possibly imaging studies to assess liver health. It’s essential to maintain communication with your healthcare provider to determine the appropriate schedule for monitoring.

In summary, your test results indicate that you have likely cleared a past Hepatitis B infection or have been vaccinated, and you are not currently infectious. Breastfeeding is safe, and you do not need the vaccine at this time. Regular follow-ups are advisable to monitor your liver health, especially if you have any risk factors or symptoms.

If you have further questions or concerns, please do not hesitate to reach out to your healthcare provider for personalized advice and guidance. Thank you for your inquiry, and I wish you the best in your health journey!

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