Medication Consultation for Anxiety: Dosage Concerns and Safety - Psychiatry

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Medication consultation


Hello doctor, I would like to ask about my current situation.
I am taking half a tablet of Mirtazapine at night, and most of the time I feel fine.
However, I occasionally experience some anxiety when I am nervous or feel unwell.
Do I need to increase my dosage to a full tablet? My weight is only 39 kilograms; would taking a full tablet be considered an overdose? How can I determine if I have taken too much, and what symptoms might occur if I do overdose?

Zhuang, 40~49 year old female. Ask Date: 2023/11/11

Dr. Wu Enliang reply Psychiatry


Hello, if you only experience anxiety occasionally when feeling nervous or unwell, it is considered normal anxiety and does not require medication.
Overmedication typically leads to drowsiness.
- Dr.
Wu Enliang

Reply Date: 2023/11/11

More Info


When it comes to managing anxiety with medication, it's crucial to consider both the dosage and the potential side effects. Based on your current situation, where you are taking half a tablet of Mirtazapine (美妥平) at night and experiencing occasional anxiety, it’s understandable to have concerns about whether to increase your dosage to a full tablet, especially given your weight of 39 kg (approximately 86 lbs).

Mirtazapine is an antidepressant that is often prescribed for anxiety and depression. The typical starting dose for adults is usually between 15 mg to 30 mg, and it can be adjusted based on individual response and tolerance. Given that you are currently taking half a tablet, it’s essential to know the strength of the tablet you are using. If it is a 15 mg tablet, you are taking 7.5 mg, which is a common starting dose. If it is a 30 mg tablet, then you are taking 15 mg, which is still within the lower range of the therapeutic dose.

Considering your weight, it is generally advisable to be cautious with medication dosages. Lower body weight can sometimes lead to a higher concentration of the drug in your system, which may increase the risk of side effects. Therefore, before making any changes to your dosage, it is essential to consult with your prescribing physician. They can assess your overall health, the severity of your anxiety symptoms, and whether an increase in dosage is warranted.

To determine if you are experiencing an overdose, it is important to be aware of the signs and symptoms. Common symptoms of Mirtazapine overdose may include:
1. Drowsiness or Sedation: An excessive amount of the medication can lead to increased sleepiness or lethargy.

2. Confusion: You may experience disorientation or difficulty concentrating.

3. Increased Heart Rate: An overdose can sometimes lead to tachycardia (rapid heartbeat).

4. Nausea or Vomiting: Gastrointestinal upset can occur with higher doses.

5. Severe Dizziness or Fainting: This can happen due to low blood pressure resulting from the medication's sedative effects.

If you notice any of these symptoms, it is crucial to seek medical attention immediately. It is also important to keep in mind that everyone reacts differently to medications, and what may be a therapeutic dose for one person could be too much for another.

In addition to medication, consider incorporating non-pharmacological strategies to manage anxiety. Techniques such as cognitive-behavioral therapy (CBT), mindfulness meditation, and regular physical activity can be beneficial in reducing anxiety symptoms. These approaches can complement your medication and may even allow for a lower dose or a gradual tapering off of medication in the future.

In summary, before making any changes to your medication regimen, consult with your healthcare provider. They can provide personalized advice based on your medical history and current health status. Monitoring your symptoms and being aware of potential overdose signs will help ensure your safety while managing anxiety effectively.

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