Do Birth Control Pills Interact with Cholesterol Medication? - Traditional Chinese Medicine

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Is there a drug interaction between the contraceptive pill (Alesse) and Simvastatin?


Hello Doctor: May I ask if there is any interaction between the contraceptive pill (Alesse) and Simvastatin? Currently, I take one Simvastatin pill in the morning and one in the evening, and I have always taken the contraceptive pill in the morning after waking up.
Is it safe to take both medications at the same time?

Frog, 20~29 year old female. Ask Date: 2023/11/13

Dr. Zhang Weidong reply Traditional Chinese Medicine


Hello, Frog: After consulting with the manufacturer of Shoumei cholesterol-lowering medication, the response was, "According to the labeling of Esliyan, there is no interaction with statin medications." Therefore, the two medications do not affect each other.
As for whether they can be taken simultaneously, since there is no evidence of interaction in studies, it is generally acceptable to take them together.
However, there is a guideline to space the administration of traditional Chinese medicine and Western medicine by one hour, so it is still recommended to wait one hour for peace of mind! I hope this answers your question! Dr.
Zhang Weidong, Department of Traditional Chinese Medicine, Changhua Hospital, Ministry of Health and Welfare.

Reply Date: 2023/11/13

More Info


When considering the interaction between birth control pills, such as Alesse (often referred to as "愛斯麗安" in Mandarin), and cholesterol medications like Simvastatin (known as "壽美降脂一號"), it is essential to understand how these medications work and their potential interactions.

Birth control pills primarily contain hormones (estrogen and progestin) that prevent ovulation and regulate menstrual cycles. On the other hand, Simvastatin is a statin medication used to lower cholesterol levels in the blood, thereby reducing the risk of heart disease and stroke.
Generally, there is no significant interaction between birth control pills and Simvastatin. Studies have shown that the use of hormonal contraceptives does not adversely affect the efficacy of statins. However, it is crucial to monitor for any side effects, as both medications can have their own set of side effects. For instance, statins can sometimes lead to muscle pain or liver enzyme elevation, while hormonal contraceptives can cause nausea, headaches, or mood changes.

It is also important to consider the overall health profile of the individual taking these medications. For example, if you have a history of liver disease, your doctor may want to monitor your liver function more closely, as both medications are metabolized in the liver. Additionally, if you are a smoker or over the age of 35, the risk of blood clots may increase when taking hormonal contraceptives, which is a separate concern but worth discussing with your healthcare provider.

In terms of timing, taking both medications at the same time (for example, in the morning) is generally acceptable. However, it is always best to follow the specific instructions provided by your healthcare provider or pharmacist. If you have any concerns about taking these medications together, or if you experience any unusual symptoms, it is advisable to consult your healthcare provider for personalized advice.

In conclusion, while there is no major interaction between birth control pills and Simvastatin, it is always prudent to maintain open communication with your healthcare provider regarding all medications you are taking. This ensures that any potential issues can be addressed promptly, and your health can be managed effectively. Always report any side effects or concerns you may have while on these medications, and ensure regular check-ups to monitor your overall health and medication efficacy.

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