Darkening Corners of the Mouth: Causes and Solutions - Dermatology

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Darkening of the corners of the mouth, worsening over time?


The darkening of the corners of the mouth seems to have started in childhood, but it has become increasingly severe until recently when I noticed it has worsened! I would like to know the possible causes and methods for improvement, as well as what should be avoided.
Thank you.

Nene, 10~19 year old female. Ask Date: 2023/11/18

Dr. Wu Yuxin reply Dermatology


It is necessary to examine the lesion in order to understand it, so it is recommended to consult a nearby dermatologist for diagnosis and treatment.

Reply Date: 2023/11/18

More Info


The darkening of the corners of the mouth, often referred to as hyperpigmentation, can be a source of concern for many individuals. This condition can manifest as dark patches or discoloration at the corners of the mouth, and it may become more pronounced over time. Understanding the potential causes and exploring possible solutions is essential for addressing this issue effectively.


Possible Causes of Darkening Corners of the Mouth
1. Hyperpigmentation: This is the most common cause of dark patches on the skin, including the corners of the mouth. Hyperpigmentation occurs when there is an excess production of melanin, the pigment responsible for skin color. Factors contributing to this condition include sun exposure, hormonal changes, and certain medications.

2. Friction or Irritation: Frequent licking of the lips, biting, or irritation from dental appliances can lead to darkening. The skin in the corners of the mouth is delicate, and constant friction can cause it to thicken and darken.

3. Nutritional Deficiencies: Deficiencies in certain vitamins, particularly Vitamin B12, Vitamin C, and folic acid, can lead to changes in skin pigmentation. A balanced diet is crucial for maintaining healthy skin.

4. Skin Conditions: Conditions such as eczema, contact dermatitis, or fungal infections can cause discoloration. If the skin is inflamed or irritated, it may respond by producing more melanin.

5. Genetics: Some individuals may be genetically predisposed to hyperpigmentation. If family members have similar discoloration, it may be a hereditary trait.

6. Underlying Health Issues: In some cases, darkening around the mouth can be a sign of underlying health issues, such as Addison's disease or other hormonal imbalances. It is essential to consult a healthcare professional if you suspect this may be the case.


Solutions and Recommendations
1. Consult a Dermatologist: The first step in addressing darkening corners of the mouth is to consult a dermatologist. They can provide a proper diagnosis and recommend appropriate treatments based on the underlying cause.

2. Topical Treatments: Over-the-counter creams containing ingredients like hydroquinone, kojic acid, or retinoids can help lighten hyperpigmented areas. However, these should be used under the guidance of a healthcare professional to avoid potential side effects.

3. Sun Protection: Protecting the skin from sun exposure is crucial. Using a broad-spectrum sunscreen with an SPF of 30 or higher can prevent further darkening and protect the skin from UV damage.

4. Moisturization: Keeping the skin hydrated can help reduce irritation and friction. Using a gentle lip balm can prevent dryness and minimize the urge to lick the lips.

5. Dietary Changes: Incorporating foods rich in vitamins and antioxidants can improve skin health. Foods high in Vitamin C (like citrus fruits), Vitamin B12 (like meat and dairy), and folic acid (like leafy greens) can be beneficial.

6. Avoid Irritants: Identifying and avoiding potential irritants, such as certain cosmetics or dental products, can help reduce inflammation and discoloration.

7. Regular Check-ups: If the darkening persists or worsens, regular follow-ups with a healthcare provider are essential to monitor the condition and adjust treatment as necessary.

In conclusion, while darkening corners of the mouth can be concerning, understanding the potential causes and exploring appropriate solutions can help manage the condition effectively. It is always advisable to seek professional medical advice for a tailored approach to treatment and care.

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