Alprazolam Use: Managing Anxiety Without Dependency - Psychiatry

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Issues related to the administration of Panadol?


I have been prone to severe anxiety since childhood (thinking the worst of situations, sweating, feeling tightness in my chest, social anxiety, and worrying about trivial matters all day).
However, I only sought help from a psychiatrist during my college years.
The doctor prescribed me Alprazolam (Xanax) and Clonazepam (Klonopin).
I stopped taking Alprazolam after a year (up until early this year).
The doctor advised me to take Clonazepam "as needed" (when anxiety affects my daily life).
Therefore, I would only take it when I was extremely anxious and could hardly cope.
Recently, due to preparing for exams and the approaching exam period, I have been taking it more frequently (one pill a day or one pill every two days).
However, today I came across a warning in the medication guide stating: "Using Alprazolam can lead to dependence; do not use high doses or use it frequently or for longer than prescribed by your doctor.
Do not take Alprazolam for more than four months without consulting your doctor, as sudden discontinuation can worsen your condition and cause withdrawal symptoms (anxiety, insomnia, irritability)." I have the following questions for Dr.
Wu:
1.
The doctor told me to take it as needed, but I have been intermittently using it for almost two years.
Does this violate the guideline stating "do not use for more than four months"? Can intermittent use lead to withdrawal symptoms?
2.
The doctor always says to take it as needed, but I am in a constant state of mild anxiety and tension throughout the day (it seems my body has gotten used to it).
I try to refrain from taking it (since it doesn't seem like it's the right time to take it) and only take it when my thoughts become overwhelming.
Is this the correct way to use the medication?
3.
What is the definition of "as needed"? (Shortness of breath? Racing thoughts? Excessive sweating? Sudden depression?) The doctor mentioned it is when anxiety affects daily life, but does my usual physical and psychological tension and racing thoughts count as affecting my life?
4.
The medication guide states that Clonazepam can lead to dependence.
If I take one to two pills daily due to excessive anxiety while preparing for exams, and then return to the original "as needed" state after the exams, will this make my anxiety worse?
I would appreciate it if Dr.
Wu could take the time to answer these questions.
Thank you.

A Xue, 20~29 year old female. Ask Date: 2023/12/03

Dr. Wu Enliang reply Psychiatry


1.
The doctor told me to take it as needed, and I have been taking it intermittently for almost two years.
Does this violate the instruction that states "do not use for more than four months"? Will intermittent use cause withdrawal symptoms? A: There is no violation; the four-month limit refers to continuous use.
2.
The doctor always says to take it as needed, but I am actually in a state of mild anxiety and tension throughout the day (it seems my body has already adapted).
I try to refrain from taking it (since it doesn't seem like a situation where I need it), and only take it when my thoughts become overwhelmingly anxious.
Is this way of using the medication correct? A: Yes, it is correct.
If possible, prioritize non-pharmacological methods, such as relaxation techniques and breathing exercises.
3.
What is the definition of "as needed"? (Shallow breathing? Racing thoughts? Sweaty palms? Sudden depression?) The doctor said it is when anxiety affects daily life, but do my regular physical and mental tension and racing thoughts count as affecting my life? A: Not entirely.
Consider it only if it affects your functional abilities.
4.
The instructions state that "Xanax can cause habituation." If I am too anxious about an upcoming exam and take one to two pills daily, then return to my original "as needed" state after the exam, will this make my anxiety worse? A: No, it will not.
Dr.
Wu En-Liang

Reply Date: 2023/12/03

More Info


Managing anxiety and insomnia can be a complex process, especially when considering the use of medications like Alprazolam (Xanax) and Escitalopram (Lexapro). Both of these medications serve different purposes and have distinct side effects and risks associated with their long-term use.


Understanding Alprazolam and Escitalopram
Alprazolam is a benzodiazepine, primarily used for the short-term management of anxiety disorders and panic attacks. It works by enhancing the effects of a neurotransmitter called gamma-aminobutyric acid (GABA), which has a calming effect on the brain. While effective for acute anxiety relief, Alprazolam carries a risk of dependency and withdrawal symptoms if used for extended periods or at high doses. The general recommendation is to use it sparingly, particularly for situational anxiety, such as before exams or significant events.

Escitalopram, on the other hand, is a selective serotonin reuptake inhibitor (SSRI) commonly prescribed for generalized anxiety disorder and depression. It works by increasing serotonin levels in the brain, which can help improve mood and reduce anxiety over time. Unlike Alprazolam, Escitalopram is not associated with a high risk of dependency, making it more suitable for long-term management of anxiety.


Addressing Your Concerns
1. Duration of Use: You mentioned that you have been using Alprazolam intermittently for nearly two years. The guideline of not using it for more than four months continuously refers to uninterrupted use. Since you are using it as needed, you are not technically violating this guideline. However, frequent use, even if not continuous, can lead to tolerance and potential withdrawal symptoms. It’s essential to discuss your usage pattern with your healthcare provider to ensure it aligns with your treatment goals.

2. Using Medication Responsibly: It’s commendable that you are trying to manage your anxiety without over-relying on medication. The concept of "using it as needed" is valid, but it can be challenging when you are in a constant state of mild anxiety. If you find yourself frequently anxious, it may be worth discussing with your doctor whether a more consistent treatment plan, possibly including Escitalopram, might be beneficial. Non-pharmacological approaches, such as cognitive-behavioral therapy (CBT), relaxation techniques, and mindfulness practices, can also be effective in managing anxiety.

3. Defining "As Needed": The term "as needed" typically refers to situations where anxiety significantly impacts your daily functioning. This could include experiencing panic attacks, severe anxiety that disrupts your ability to work or study, or physical symptoms like shortness of breath or excessive sweating. If your anxiety is consistently affecting your quality of life, it may be time to reevaluate your treatment strategy with your healthcare provider.

4. Habit Formation and Exam Anxiety: If you find yourself needing to take Alprazolam daily due to increased anxiety from upcoming exams, it’s crucial to monitor how this affects your overall anxiety levels. While it may provide temporary relief, relying on it during stressful periods can lead to increased anxiety in the long run, especially if you develop a dependency. After your exams, consider tapering off the medication under your doctor’s guidance and exploring other coping mechanisms for anxiety.


Alternative Strategies
In addition to medication, consider incorporating lifestyle changes and therapeutic approaches to manage anxiety and insomnia effectively:
- Regular Exercise: Physical activity can significantly reduce anxiety levels and improve sleep quality.

- Healthy Sleep Hygiene: Establish a consistent sleep schedule, create a relaxing bedtime routine, and limit screen time before bed.

- Mindfulness and Relaxation Techniques: Practices such as yoga, meditation, and deep-breathing exercises can help reduce anxiety and improve sleep.

- Cognitive Behavioral Therapy (CBT): This form of therapy is effective in treating anxiety and can provide you with tools to manage your thoughts and feelings more effectively.


Conclusion
Managing anxiety and insomnia is a multifaceted process that often requires a combination of medication, therapy, and lifestyle changes. While Alprazolam can be effective for short-term relief, it’s essential to use it judiciously to avoid dependency. Regular consultations with your healthcare provider can help you navigate your treatment options and find the most effective strategies for your specific situation.

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