What is the relationship between Candida albicans and chronic prostatitis in terms of antibiotics?
1.
At the beginning of September, three days after having sexual intercourse with my wife, I experienced pain at the urethral opening during urination, redness and itching of the glans, and white scaling around the outer edge.
I went to a local hospital where Dr.
A suggested it might be balanitis and prescribed Four Benefits cream for the glans, Blessing capsules, and antibiotics and painkillers for seven days.
The next day, my wife also had symptoms of vaginitis and went to see a gynecologist, where she was diagnosed with a Candida infection and prescribed suppositories and medication.
After completing our respective treatments, we both recovered.
2.
In mid-November, I experienced pain at the base of the penis after urination, so I returned to the local hospital.
Dr.
B reviewed my blood and urine test results from September, which primarily checked for sexually transmitted infections and showed normal results.
Dr.
B prescribed enteric-coated doxycycline capsules (an antibiotic) for seven days.
During the seven days of medication, I felt that the pain at the base of the penis worsened, and I also developed intermittent mild pain in the testicles and pain during ejaculation.
3.
At the end of November, due to the increase in symptoms after completing the medication, I went to the local hospital and switched to Dr.
C.
The doctor suggested it might be chronic prostatitis.
Dr.
C examined the glans and testicles, which appeared normal, and prescribed Silodosin and painkillers for five days, along with tests for PSA, IgE, and CRP.
After five days of Silodosin, the pain symptoms improved, but after five days, I started experiencing pain at the base of the penis after urination, intermittent mild testicular pain (sometimes on the left, sometimes on the right), and pain at the base of the penis after ejaculation.
I returned to Dr.
C, who conducted a uroflowmetry test (which was normal) and noted that the previous PSA, IgE, and CRP results were also normal.
Dr.
C then prescribed Silodosin and painkillers for another 14 days.
While taking the painkillers for 14 days, the pain symptoms improved, but after finishing the 14 days, I still had mild pain at the base of the penis after urination, intermittent mild testicular pain, and pain at the base of the penis after ejaculation.
I also noticed discomfort when sitting if pressure was applied to the testicles.
I purchased a multivitamin with zinc and took it for three days, which reduced the pain at the base of the penis, intermittent testicular pain, and pain after ejaculation.
4.
Although the aforementioned symptoms have decreased, I have not fully recovered.
In mid-December, I switched to Dr.
D at a large teaching hospital.
Dr.
D also examined the glans and testicles and I described my previous medical history.
Currently, my symptoms include mild pain at the base of the penis after urination, intermittent testicular pain (sometimes on the left, sometimes on the right), and pain at the base of the penis after ejaculation.
I also mentioned that I had a hernia several years ago and underwent bilateral groin repair surgery (the discomfort in the testicles feels similar to the pulling sensation I had during the hernia).
The doctor indicated that this should not be related to the hernia surgery and is more likely a chronic condition.
Blood and urine tests were conducted, but I have not returned for results yet.
The doctor prescribed Hiberix enteric-coated tablets and anti-inflammatory painkillers for ten days.
After taking the medication for three days, I felt no improvement; in fact, the pain slightly worsened, and my testicles became more sensitive, causing discomfort when sitting.
Additionally, I experienced a new stinging sensation in the penis.
I was originally scheduled for a follow-up in five days, but I plan to return earlier.
Based on my medical history, I conclude that aside from the improvement from the antibiotics and painkillers for balanitis in early September (which could also be due to the topical cream), the pain has worsened with different antibiotics prescribed by different doctors in mid-November and recently in mid-December.
However, the Silodosin prescribed by Dr.
C was effective, although prolonged use caused lower back pain.
I would like to ask Dr.
D whether I might have chronic prostatitis that is non-bacterial, or if it is possible that the Candida infection diagnosed in September has led to chronic prostatitis, causing the pain to worsen with antibiotic treatment.
I have read that certain antibiotics may promote Candida overgrowth.
Based on the above description, would you recommend antifungal treatment or suggest other diagnostic or treatment options? Thank you.
Mi Tang, 30~39 year old female. Ask Date: 2023/12/28
Dr. Du Shixi reply Urology
Hello: Your symptoms seem to indicate chronic prostatitis.
However, chronic, non-bacterial prostatitis is inherently difficult to treat and diagnose.
The use of antibiotics is almost always recommended.
Please discuss this with your physician during your follow-up visit.
Additionally, it is important to pay attention to your lifestyle.
You can refer to https://www.shutien.org.tw/dr_doc_detail.aspx?bookid=60 for more information.
Reply Date: 2023/12/28
More Info
The relationship between Candida infection and chronic prostatitis is a complex topic that warrants careful consideration. Based on your detailed medical history, it appears that you have been experiencing a range of symptoms that could be indicative of chronic prostatitis, potentially exacerbated by a Candida infection.
Chronic prostatitis, particularly the non-bacterial type, can be challenging to diagnose and treat. It is characterized by pelvic pain and urinary symptoms without evidence of a urinary tract infection. Your symptoms, including pain at the base of the penis, testicular discomfort, and pain during ejaculation, align with those commonly reported in chronic prostatitis cases.
The initial episode of pain and discomfort following sexual intercourse, along with the subsequent diagnosis of a Candida infection in your wife, raises the possibility of a sexually transmitted infection or a related inflammatory response. Candida, a type of yeast, can indeed cause infections in both men and women, leading to symptoms such as itching, redness, and discomfort in the genital area. While Candida infections are more commonly associated with vulvovaginal candidiasis in women, men can also experience balanitis (inflammation of the glans) due to Candida, which could explain your initial symptoms.
The treatment you received, including antibiotics and antifungal medications, may have had mixed results. Antibiotics can disrupt the normal flora of the body, potentially allowing for an overgrowth of Candida, which could explain why your symptoms worsened after antibiotic treatment. This phenomenon is known as antibiotic-associated candidiasis. In your case, the use of antibiotics may have inadvertently contributed to the persistence of your symptoms by allowing Candida to proliferate.
Given your ongoing symptoms and the lack of significant improvement with antibiotic therapy, it may be prudent to consider antifungal treatment. This could help address any underlying Candida overgrowth that may be contributing to your chronic prostatitis symptoms. Additionally, it is essential to evaluate whether there are any other underlying conditions, such as pelvic floor dysfunction or nerve entrapment, that could be contributing to your discomfort.
In terms of further evaluation, it would be beneficial to conduct a thorough examination, including a urinalysis and possibly a culture to check for Candida or other pathogens. A referral to a urologist or an infectious disease specialist who has experience with chronic prostatitis and fungal infections may also provide additional insights and treatment options.
In summary, while your symptoms may suggest chronic prostatitis, the potential role of Candida infection should not be overlooked. It is essential to approach your treatment holistically, considering both the possibility of fungal overgrowth and other contributing factors. A tailored treatment plan that includes antifungal therapy, lifestyle modifications, and possibly physical therapy for pelvic floor dysfunction may provide relief and improve your quality of life. Regular follow-ups with your healthcare provider will be crucial to monitor your progress and adjust your treatment as necessary.
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