Mitral Valve Prolapse and Its Impact on Heart Health - Cardiology

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Mild mitral valve prolapse + exercise electrocardiogram?


Hello Doctor: My cholesterol level is 241, and my low-density lipoprotein (LDL) cholesterol is 171.
I have not taken any lipid-lowering medications for five years.
My father has a history of hypertension, diabetes, and hyperlipidemia.
Recently, I have experienced chest tightness and slight heart pain, along with elevated blood pressure for two weeks.
I underwent a cardiac ultrasound, color Doppler echocardiography, and exercise electrocardiogram testing.
The cardiac structure showed no issues, but a mild mitral valve prolapse was detected, and the exercise ECG indicated slight myocardial ischemia (coronary vasospasm).
The doctor mentioned that mitral valve prolapse can often lead to myocardial ischemia, but I found information suggesting that myocardial ischemia could indicate possible obstruction in the coronary arteries.
Does this mean I could have coronary artery disease? Would you recommend self-paying for a cardiac CT scan, carotid ultrasound, and peripheral vascular examination? Or should I go to a medical center for a repeat cardiac ultrasound and exercise ECG? Since I am planning to undergo in vitro fertilization, I want to actively address my heart health.
Thank you in advance for your response.
Attached are the results of my exercise ECG test: Height: 157 cm, Weight: 48 kg, Systolic Blood Pressure: 136 mmHg, Diastolic Blood Pressure: 94 mmHg, Heart Rate: 66 BPM, Clinical Diagnosis: Coronary Artery Disease, Indication: Chest Tightness, Current Medication: Unknown, Underlying Disease: Hyperlipidemia, Risk Factor for CAD: Hyperlipidemia, Family History: Positive.
Resting ECG: Non-specific ST-T changes, Sinus Rhythm.
Previous Test: Nil.
Summary of Exercise Test: Protocol: Treadmill Standard Bruce, MHR-Predicted: Above 85%, Exercise Time: 10’31”, Max Speed: 6.80 km/h, Max Grade: 16.0%, METs Achieved: 13.50 METs, Peak Heart Rate: 171 bpm, % Max Heart Rate: 91%, Resting Blood Pressure: 136/94 mmHg, Peak Systolic Blood Pressure: 208 mmHg, Termination Reasons: Shortness of Breath.
ECG Lead Change During Exercise Test: ECG Lead Involving:

Sha Sha, 30~39 year old female. Ask Date: 2024/01/04

Dr. Li Han reply Cardiology


Hello, regarding your inquiry, you are experiencing chest tightness and stabbing pain; however, the exercise electrocardiogram was able to complete the fourth stage of the BRUCE protocol, showing only exercise-induced dyspnea without the aforementioned chest tightness symptoms.
Functionally, your cardiovascular risk assessment appears to be in the low-risk category, so there is no need for immediate concern.
For long-term risks related to coronary artery disease or atherosclerotic cardiovascular disease, you may refer to the Framingham Risk Score to estimate your risk.
Your elevated lipid levels are another risk indicator.
Additionally, the coronary artery calcium score can serve as a reference, but this indicator may be overestimated in individuals under 40 years old (for men aged 40 or women post-menopause, or in diabetic patients, assessment may be done 5 years earlier).
Managing risk factors is a lifelong commitment.
For further details, please consult your family physician.
Take care from Changhua Hospital, Ministry of Health and Welfare.

Reply Date: 2024/01/04

More Info


Mitral Valve Prolapse (MVP) is a condition where the mitral valve, which separates the left atrium from the left ventricle, does not close properly. This can lead to mitral regurgitation, where blood leaks backward into the left atrium during heart contractions. MVP is often benign and may not cause significant symptoms or complications for many individuals. However, in some cases, it can be associated with palpitations, chest pain, and even anxiety.
In your case, the presence of mild mitral valve prolapse, along with symptoms such as chest tightness and slight heart pain, raises some important considerations regarding your heart health. Your elevated cholesterol levels and family history of hypertension and hyperlipidemia are significant risk factors for coronary artery disease (CAD). While MVP itself does not directly cause coronary artery disease, it can be associated with symptoms that mimic ischemia, such as the chest discomfort you are experiencing.

The exercise stress test indicating some myocardial ischemia suggests that there may be episodes where your heart muscle is not receiving enough oxygen, which can be due to various reasons, including coronary artery spasms or blockages. It is crucial to differentiate between symptoms caused by MVP and those stemming from potential coronary artery issues.
Given your symptoms and the results of your tests, it is advisable to take a proactive approach to your heart health. Here are some recommendations:
1. Further Evaluation: Considering your symptoms and the findings from your tests, it would be prudent to undergo further evaluation. A coronary CT angiogram can provide detailed images of your coronary arteries and help identify any blockages or significant narrowing. This non-invasive test can be particularly useful in assessing your risk for CAD.

2. Lifestyle Modifications: Since you have elevated cholesterol levels, adopting a heart-healthy lifestyle is essential. This includes a diet low in saturated fats and cholesterol, regular physical activity, maintaining a healthy weight, and avoiding smoking. These changes can help manage your cholesterol levels and reduce your overall cardiovascular risk.

3. Regular Monitoring: Given your family history and current symptoms, regular follow-ups with your healthcare provider are crucial. Monitoring your blood pressure, cholesterol levels, and overall heart health will help in early detection of any potential issues.

4. Medication Consideration: Discuss with your physician the possibility of starting lipid-lowering medications, especially if lifestyle changes alone do not adequately control your cholesterol levels. Statins or other medications may be indicated based on your overall risk profile.

5. Consultation with a Cardiologist: Given your complex situation, a referral to a cardiologist for a comprehensive evaluation may be beneficial. They can provide insights into the relationship between your MVP, symptoms, and any potential coronary artery disease.

6. Stress Management: Since anxiety can exacerbate symptoms related to MVP, consider incorporating stress management techniques such as mindfulness, yoga, or counseling into your routine.

In summary, while mitral valve prolapse can contribute to symptoms of chest discomfort, it is essential to rule out other potential causes, especially given your risk factors. Taking proactive steps towards evaluation and management can help ensure your heart health is optimized, particularly as you plan for future family growth through assisted reproductive technologies. Always consult your healthcare provider before making any changes to your health regimen.

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