Brain Hemorrhage: Why Angiography Might Miss the Bleeding Point - Neurosurgery

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Cerebral hemorrhage underwent cerebral angiography, but no bleeding source (aneurysm) was found?


Hello doctor, my sister was hospitalized on the night of January 2 due to a cerebral hemorrhage and underwent a craniotomy for drainage.
She is currently in the intensive care unit, and her blood pressure and intracranial pressure are normal.
A cerebral angiography was scheduled for January 3, but no bleeding point (aneurysm) was found.
Another angiography is scheduled for January 10.
I was not present at the time and could not ask the attending physician, so I am searching online for answers to the following questions: 1.
Why might the bleeding point not be found? 2.
Why is there such a long wait, and what impact could this have? 3.
If no bleeding point is found, what other methods can be used for management? Thank you.

Que Xianglin, 40~49 year old female. Ask Date: 2024/01/05

Dr. Zhao Shaoqing reply Neurosurgery


This needs to be evaluated based on the report and the judgment at that time.
You can visit the outpatient clinic for consultation.

Reply Date: 2024/01/05

More Info


Understanding brain hemorrhage and the challenges associated with identifying the source of bleeding is crucial for effective management and treatment. In your sister's case, where a brain hemorrhage occurred and subsequent angiography failed to locate the bleeding point, several factors could contribute to this situation.

1. Why Might Angiography Miss the Bleeding Point?
Angiography is a specialized imaging technique used to visualize blood vessels and can be very effective in identifying abnormalities such as aneurysms or arteriovenous malformations (AVMs). However, there are several reasons why it might not detect the source of bleeding:
- Timing of the Procedure: If the angiography is performed too soon after the hemorrhage, the blood may still be pooling in the surrounding tissue, obscuring the view of the vessels. Additionally, if the bleeding has stopped, the angiogram may not show any active bleeding.

- Size and Location of the Lesion: Small vascular malformations or those located in difficult-to-access areas of the brain may not be easily visualized. Aneurysms can also be small and may not be detected if they are not actively bleeding.

- Technical Limitations: The quality of the imaging equipment and the skill of the operator can also affect the results. Sometimes, the contrast agent may not adequately fill the vessels, leading to missed diagnoses.

2. What Are the Implications of Waiting for Further Testing?
The decision to wait for a repeat angiography can be concerning, especially after a significant event like a brain hemorrhage. However, there are several reasons for this approach:
- Monitoring Recovery: If your sister's vital signs (blood pressure and intracranial pressure) are stable, it may indicate that the immediate risk has decreased, allowing for careful monitoring before further invasive procedures.

- Risk Assessment: The medical team may want to assess whether the bleeding is likely to recur or if the initial hemorrhage was an isolated incident. This can help in deciding the urgency of further interventions.

- Potential Complications: Waiting too long can lead to complications, such as rebleeding or increased intracranial pressure, which can affect recovery. Continuous monitoring is essential to mitigate these risks.

3. What Other Methods Can Be Used If the Bleeding Point Remains Unidentified?
If angiography does not reveal the source of the hemorrhage, other diagnostic methods may be considered:
- CT or MRI Scans: These imaging techniques can provide additional information about the brain's structure and any potential areas of concern that may not be visible on angiography.

- Repeat Angiography: As planned in your sister's case, repeating the angiography after some time may yield different results, especially if the bleeding has resolved or if the condition of the blood vessels has changed.

- Surgical Exploration: In some cases, if a vascular malformation is strongly suspected but not confirmed through imaging, a neurosurgeon may consider surgical exploration to directly visualize and address the issue.

In conclusion, while it can be frustrating and concerning when a bleeding point is not identified, it is essential to trust the medical team's judgment and the rationale behind their approach. Continuous monitoring and follow-up imaging are critical components of managing brain hemorrhages. If you have further questions or concerns, it is advisable to discuss them directly with your sister's healthcare providers, who can offer specific insights based on her condition and treatment plan.

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