Renal failure
Frequent urination at night, dry mouth, presence of protein in urine, BUN 40, creatinine 4.1.
What measures can be taken to control the rise in creatinine levels and improve frequent urination and dry mouth? Currently taking Ketosteril (an amino acid supplement), is it safe for long-term use? Thank you!
Weng Xiansheng, 60~69 year old female. Ask Date: 2004/02/05
Dr. Yang Jun reply Internal Medicine
Hello: In response to your question, it is noted that kidney function has deteriorated to the level of chronic kidney failure, which can lead to symptoms such as frequent urination, nocturia, and proteinuria.
At this stage, it is essential to regularly follow up with a nephrologist for outpatient care and medication management, and to avoid taking traditional Chinese medicine or any unverified medications and supplements recommended by others.
It is also important to monitor blood pressure and adopt a low-protein diet to potentially slow the progression of kidney function deterioration.
As for Ketosteril, it is a medication containing amino acids that can promote protein synthesis in the body and is acceptable for the treatment of patients with chronic kidney failure, but it should only be taken under the guidance of a nephrologist based on clinical conditions.
Reply Date: 2004/02/05
More Info
Managing kidney failure, particularly when it leads to symptoms like frequent urination, dry mouth, and elevated creatinine levels, requires a comprehensive approach that involves dietary modifications, medication management, and regular monitoring of kidney function. Given your current situation, where you are experiencing frequent urination at night, dry mouth, and protein in your urine, along with elevated blood urea nitrogen (BUN) and creatinine levels, it’s crucial to address these issues systematically.
Understanding Your Symptoms
1. Frequent Urination and Dry Mouth: These symptoms can be attributed to kidney dysfunction, which affects the body’s ability to concentrate urine. As kidney function declines, the kidneys may struggle to retain water, leading to increased urine output, especially at night (nocturia). Dry mouth can also be a result of dehydration or the body’s response to kidney issues.
2. Elevated Creatinine and BUN: Creatinine is a waste product that is normally filtered out by the kidneys. Elevated levels indicate that the kidneys are not functioning optimally. BUN is another marker of kidney function and can rise due to dehydration, high protein intake, or kidney dysfunction.
3. Proteinuria: The presence of protein in urine is a sign of kidney damage. It indicates that the filtering units of the kidneys (glomeruli) are not functioning properly.
Management Strategies
1. Dietary Modifications:
- Low-Protein Diet: Since you are experiencing kidney failure, it is essential to limit protein intake to reduce the workload on your kidneys. This can help lower creatinine levels and minimize proteinuria. Consult with a renal dietitian to create a personalized meal plan.
- Hydration: While it may seem counterintuitive, maintaining adequate hydration is crucial. However, fluid intake should be monitored based on your kidney function and any restrictions advised by your healthcare provider.
- Sodium and Potassium Control: Limit sodium intake to help manage blood pressure and reduce fluid retention. Potassium levels should also be monitored, as impaired kidney function can lead to elevated potassium levels, which can be dangerous.
2. Medication Management:
- Ketosteril: This medication is a mixture of essential amino acids and is often used in patients with chronic kidney disease to help manage protein intake while providing necessary nutrients. It can be beneficial in preventing malnutrition in patients with kidney failure. However, long-term use should be monitored by a nephrologist to ensure it is appropriate for your specific condition.
- Regular Monitoring: Frequent check-ups with your nephrologist are essential. They will monitor your kidney function, adjust medications as necessary, and provide guidance on managing your symptoms.
3. Lifestyle Changes:
- Blood Pressure Management: High blood pressure can worsen kidney function. Regular monitoring and adherence to prescribed antihypertensive medications are crucial.
- Avoiding Nephrotoxic Substances: Stay away from non-steroidal anti-inflammatory drugs (NSAIDs) and certain antibiotics that can further damage the kidneys.
4. Symptom Management:
- Dry Mouth: To alleviate dry mouth, consider sipping water throughout the day, using saliva substitutes, or chewing sugar-free gum to stimulate saliva production.
- Frequent Urination: Discuss with your doctor the possibility of medications that can help manage nocturia, such as desmopressin, which can reduce nighttime urine production.
Conclusion
In summary, managing kidney failure and its associated symptoms requires a multifaceted approach that includes dietary changes, medication management, and regular monitoring. It is essential to work closely with your healthcare team, particularly a nephrologist, to tailor a treatment plan that addresses your specific needs. While Ketosteril can be beneficial, its long-term use should be evaluated regularly. Always consult your healthcare provider before making any changes to your treatment plan.
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