Prolonged Blurriness After Pupil Dilation in Diabetic Patients - Ophthalmology

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Pupil Dilation Issues


Hello, doctor.
I have undergone vitrectomy in both eyes due to diabetic proliferative retinopathy.
Currently, I still have silicone oil in my eyes.
I would like to ask: the hospital states that the effect of the dilating drops generally lasts for 4-6 hours, but my vision remains blurry even after 6 hours! Usually, it takes until the next day for my vision to return to normal.
What could be the reason for this situation? Thank you.

Cai Xiansheng, 40~49 year old female. Ask Date: 2024/01/20

Dr. Gao Pilin reply Ophthalmology


Hello: For diabetic patients, the slower recovery from mydriasis may be due to the effects of diabetes on the optic nerve and ocular tissues.
This could include a slowdown in nerve conduction velocity or vascular issues that affect the normal constriction and dilation response of the pupils.
Additionally, intraocular silicone oil may influence the metabolism and excretion of mydriatic agents, thereby prolonging the mydriatic effect.
However, if the condition resolves by the next day, it indicates that metabolism is still occurring, just at a slower rate, so there is no need for excessive concern.

Reply Date: 2024/01/20

More Info


Prolonged blurriness after pupil dilation, especially in diabetic patients who have undergone vitrectomy and have silicone oil in their eyes, can be concerning. In your case, it is important to consider several factors that may contribute to this phenomenon.

Firstly, the medications used for dilation, typically tropicamide or phenylephrine, can cause varying degrees of pupil dilation and may lead to blurred vision. In most individuals, the effects of these medications wear off within a few hours. However, in patients with underlying conditions such as diabetes, especially those who have had surgical interventions like vitrectomy, the recovery time may be prolonged. This can be due to several reasons:
1. Silicone Oil Presence: The presence of silicone oil in the eye can affect the optical properties of the eye. Silicone oil can create a refractive error, leading to blurred vision. This is particularly true if the oil is not perfectly clear or if there are any bubbles or impurities within it. The optical clarity of the silicone oil can also be influenced by the surrounding tissues and the state of the retina.

2. Diabetic Retinopathy: Diabetic retinopathy can cause changes in the retina that may affect vision. Even after surgery, the retina may still be healing or may have residual effects from the disease. This can lead to fluctuations in vision, especially after procedures that involve dilation.

3. Post-Surgical Changes: After vitrectomy, the eye undergoes a healing process that can take time. Changes in the vitreous cavity and the retina can lead to temporary visual disturbances. The healing process may also be influenced by the presence of silicone oil, which can alter the normal anatomy and physiology of the eye.

4. Intraocular Pressure (IOP): After dilation and surgical procedures, changes in intraocular pressure can occur. Elevated IOP can lead to blurred vision and discomfort. It is essential to monitor IOP, especially in diabetic patients, as they are at a higher risk for glaucoma.

5. Corneal Edema: Dilation can sometimes exacerbate pre-existing corneal issues, such as edema, which can lead to blurred vision. Diabetic patients are more prone to corneal complications, and any additional stress on the eye can worsen these conditions.

6. Systemic Factors: Diabetes can affect the overall health of the eye, including the lens and cornea. If blood sugar levels are not well controlled, this can lead to temporary changes in vision, including prolonged blurriness.

Given these factors, it is not uncommon for some patients, especially those with a history of diabetic retinopathy and surgical interventions, to experience prolonged blurriness after pupil dilation. If your vision does not return to normal after a reasonable period, or if you experience any other concerning symptoms such as pain, increased redness, or significant changes in vision, it is crucial to follow up with your ophthalmologist. They may want to perform a thorough examination to rule out any complications related to your surgery or the effects of diabetes on your eyes.

In summary, while prolonged blurriness after dilation can be expected in some cases, especially with your medical history, it is essential to monitor your symptoms and maintain regular follow-ups with your eye care provider to ensure optimal management of your condition.

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