Can You Drink Alcohol While Undergoing Treatment for Polymyositis? - Internal Medicine

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Is it safe to consume alcohol during the treatment of polymyositis?


Hello, doctor.
I am currently being treated for polymyositis with the following medications:
===================================
* Azathioprine 50 mg (Azaprine) - one tablet per day
* Donisone - four tablets per day
===================================
Previously, during a more severe phase of my condition, I received intravenous cyclophosphamide treatment (three doses), and I am no longer receiving continuous injections.
My condition is now stable and under control, and I am gradually (monthly) reducing the dosage of corticosteroids.
Given my current situation, is it permissible to have a small drink during the treatment period? (For example, a glass of red wine or beer, not excessive drinking), or is it strictly prohibited to consume alcohol?

Peter, 40~49 year old female. Ask Date: 2024/01/24

Dr. Gao Jiankai reply Internal Medicine


Hello, thank you for your inquiry.
Your current dosage of steroids is still high, so it is advisable to avoid alcohol for now.
Once your steroid dosage is reduced to two pills or less per day, please discuss it with your physician.
This is from the Allergy, Immunology, and Rheumatology Department of Changhua Hospital, Ministry of Health and Welfare.
We care about your well-being.

Reply Date: 2024/01/24

More Info


When it comes to consuming alcohol while undergoing treatment for polymyositis, it is essential to consider several factors, including the medications you are taking, your overall health status, and the potential interactions between alcohol and these medications.

Polymyositis is an inflammatory muscle disease that requires careful management, often involving immunosuppressive medications. In your case, you are currently taking Azathioprine (抑妙寧膜衣錠) and Donisone (樂爾爽錠), which is a corticosteroid. Azathioprine is an immunosuppressant that can increase your risk of infections and may have liver toxicity. Corticosteroids, while effective in managing inflammation, can also have various side effects, including effects on your liver and metabolism.

Given that you are on Azathioprine and Donisone, it is generally advisable to limit or avoid alcohol consumption. Alcohol can exacerbate the side effects of these medications, particularly in terms of liver function. Both Azathioprine and corticosteroids can affect liver enzymes, and alcohol can further stress the liver, potentially leading to complications. Additionally, alcohol can impair your immune system, which is already compromised due to the medications you are taking.

Moreover, while you mentioned that your condition is stable and you are gradually reducing your steroid dosage, it is crucial to consult with your healthcare provider before making any decisions about alcohol consumption. They can provide personalized advice based on your specific health status, the dosage of your medications, and any other underlying health conditions you may have.

In general, if you are considering having a small drink, such as a glass of wine or beer, it is best to wait until your healthcare provider gives you the green light, especially if your steroid dosage is still significant. Once your steroid dosage decreases to a lower level, such as two pills a day or less, it may be more acceptable to discuss the possibility of moderate alcohol consumption with your doctor.

In summary, while the idea of enjoying a small drink may seem appealing, the potential risks associated with alcohol consumption while on immunosuppressive therapy cannot be overlooked. It is always better to err on the side of caution and prioritize your health. Regular follow-ups with your healthcare provider will help ensure that you are managing your condition effectively and safely. If you have any further questions or concerns, do not hesitate to reach out to your healthcare team for guidance.

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