Blood disorders
Hello, Doctor: Last week, I visited the hospital due to feeling unwell, and the doctor conducted a blood test.
The report is as follows: Lymphocyte 22% [19][48], MCH (Mean Corpuscular Hemoglobin) 31.4 g/dL [33][37], MCH 29.0 pg [27][31], MCHC (Mean Corpuscular Hemoglobin Concentration) 31.4 g/dL [33][37], MCV (Mean Corpuscular Volume) 92.3 fL [80][99], MPV (Mean Platelet Volume) 10.5 fL [7.400][10.400], Monocyte 4% [0][9], Neutrophil Band 0% [0][6], Neutrophil Segmented 71% [40][74], Platelet 26.2 *10^4/uL [13][40], RBC (Red Blood Cell) 414 *10^4/uL [420][540], RDW-CV (Red Cell Distribution Width) 13.8% [11.50][14.50], Hemoglobin 12.0 g/dL [12][16], WBC (White Blood Cell) 7870/uL [4500][10000], ANC (Absolute Neutrophil Count) 5588/uL [1490][4680], Basophil 1% [0][1], Hematocrit 38.2% [37][47], Eosinophil 2% [0][4], Basophil 1% [0][1].
The values marked with an asterisk (*) are abnormal.
The doctor mentioned that I have a slight anemia, but it's only a little.
He prescribed B vitamins for me, so I would like to ask if further blood tests are necessary? (Last month, I had a physical examination, and my red blood cell count was normal, so this time it is 414, which is slightly low, and I am unsure if it indicates a problem.) Additionally, I would like to inquire about the MCHC, which was slightly low in both tests, the first being 32.8 and the second 31.4, both highlighted in red.
Is there an issue with this? Lastly, regarding the MPV of 10.5 (range [7.400][10.400]), what does this indicate? Thank you for your assistance, Doctor.
EMILY, 30~39 year old female. Ask Date: 2024/02/04
Dr. Lin Zhebin reply Family Medicine
Hello: Based on your blood test report, although the RBC is low, the Hemoglobin is within the normal range, so the anemia is likely not severe.
Further analysis of the low MCH and low MCHC suggests that it may be microcytic anemia, with the most common cause being iron deficiency anemia.
If you wish to investigate further, you may consider tests related to iron deficiency anemia.
Additionally, the slightly elevated MPV should not be a major concern.
Reply Date: 2024/02/04
More Info
Understanding blood test results can be daunting, especially when faced with various medical terminologies and numbers that may seem overwhelming. In your case, the blood test results indicate several parameters that require careful interpretation. Let’s break down the key components of your report and address your concerns.
1. Lymphocyte and Neutrophil Counts: Your lymphocyte percentage is at 22%, which falls within the normal range (19-48%). Lymphocytes are crucial for your immune response, and a normal count suggests that your immune system is functioning adequately. The neutrophil count is at 71%, which is slightly elevated compared to the normal range (40-74%). Neutrophils are the first line of defense against infections, and an increase can indicate an ongoing infection or inflammation. However, since your overall white blood cell (WBC) count is within normal limits (7,870/uL), this may not be a cause for concern.
2. Red Blood Cell (RBC) and Hemoglobin Levels: Your RBC count is at 414 *10^4/uL, which is slightly below the normal range (420-540 *10^4/uL). This could indicate a mild form of anemia, especially since your hemoglobin level is at 12.0 g/dL, which is also on the lower side of the normal range (12-16 g/dL). Anemia can result from various factors, including nutritional deficiencies (like iron or vitamin B12), chronic diseases, or bone marrow issues. The doctor’s decision to prescribe B vitamins suggests a focus on potential nutritional causes, which is a reasonable first step.
3. MCHC (Mean Corpuscular Hemoglobin Concentration): Your MCHC values of 32.8 and 31.4 g/dL are slightly below the normal range (33-37 g/dL). MCHC measures the average concentration of hemoglobin in red blood cells. Low MCHC can indicate hypochromic anemia, often associated with iron deficiency. It’s essential to monitor this parameter, especially if your hemoglobin levels continue to trend downward.
4. MPV (Mean Platelet Volume): Your MPV is at 10.5 fL, which is slightly above the normal range (7.4-10.4 fL). MPV indicates the average size of platelets in your blood. Larger platelets are often younger and can indicate increased platelet production, which may occur in response to various conditions, including inflammation or recovery from blood loss. While this value is not alarming, it should be interpreted in conjunction with your overall health status and any symptoms you may be experiencing.
5. Follow-Up Testing: Given that your RBC and hemoglobin levels are slightly low, and considering the MCHC values, it may be prudent to follow up with additional tests. These could include iron studies (serum iron, ferritin, total iron-binding capacity) to assess for iron deficiency, or vitamin B12 and folate levels to rule out nutritional deficiencies. If symptoms persist or worsen, further investigation into potential underlying causes, such as chronic disease or bone marrow function, may be warranted.
In summary, while your blood test results indicate some mild abnormalities, they do not necessarily point to a severe underlying condition. The slight anemia and low MCHC are worth monitoring, and the prescription of B vitamins is a good initial approach. It’s essential to maintain open communication with your healthcare provider, follow their recommendations, and consider follow-up testing to ensure your health remains on track. If you have any further questions or concerns, don’t hesitate to reach out to your doctor for clarification and guidance.
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