Genital Warts: Testing, Treatment, and Relationship Concerns - Urology

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Genital warts


Hello Dr.
Du: My spouse was diagnosed with genital warts at the end of August 2023 and immediately underwent laser removal of the lesions.
Since the wound has healed, there have been no visible new lesions.
In early February 2024, an HPV DNA test (urine sample) was conducted, and the results were negative for the virus.
I also visited a gynecologist at the end of August 2023 after informing them of my spouse's condition, where I underwent a pelvic examination, a Pap smear, and an HPV DNA test.
The Pap smear results were within normal limits.
The HPV DNA test detected only type 52, and the doctor indicated that there was no infection with genital warts.
To date, no lesions have been found, and in early February 2024, I had another Pap smear and HPV DNA test (the report is still pending).
During the pelvic examination, the gynecologist found no lesions or abnormalities.
(Since the end of August 2023, my partner and I have not engaged in sexual intercourse, and we both received the 9-valent vaccine, currently having completed the second dose.) I am still very anxious and would like to ask you a few questions: 1.
Do the above tests confirm that I am not infected? What else can I do? 2.
How long do you recommend waiting before resuming sexual activity? Is it safe to have unprotected sex with my partner? (Can we still plan for pregnancy?) 3.
Does my partner still need to undergo an HPV DNA test (the type that uses a brush to collect samples from the penis)?

anonym, 30~39 year old female. Ask Date: 2024/02/17

Dr. Du Shixi reply Urology


Hello:
1.
Can the above tests confirm that I am not infected? What else can I do? --- It is not 100% certain, but the likelihood is very high.
What you can do is to monitor and have regular check-ups.
2.
How long after can I resume sexual activity? Is it safe to have unprotected sex with my partner? (Can we still plan for pregnancy?) --- In some cases, it may take over a year.
If you have plans for pregnancy, please consult an obstetrician.
3.
Does my partner still need to undergo HPV DNA testing? (The type that uses a brush to collect samples from the penis?) --- It can be done, but it can only serve as a reference.
Wishing you good health.
Regarding the HPV DNA test that only detected type 52, the doctor indicated no infection with genital warts --- Was that a mistake? There should be an infection with HPV type 52.

Reply Date: 2024/02/17

More Info


Understanding genital warts, particularly in the context of HPV (human papillomavirus) infection, is crucial for both physical health and emotional well-being. Your situation raises several important questions regarding testing, treatment, and relationship concerns, especially after your partner's diagnosis and subsequent treatment.

1. Testing and Infection Status: Based on the information provided, it appears that you have undergone thorough testing, including a Pap smear and HPV DNA testing. The fact that your Pap smear results were normal and that your HPV DNA test only detected HPV type 52 (which is not typically associated with genital warts) suggests that you likely do not have an active infection with the types of HPV that cause genital warts (primarily types 6 and 11). However, it is important to note that HPV can remain dormant in the body for years, and not all strains are tested in standard screenings. If you are concerned about your HPV status, you might consider discussing with your healthcare provider the possibility of additional testing or monitoring.

2. Timing for Resuming Sexual Activity: Generally, it is advisable to wait until both partners have been cleared of any active HPV infection and have completed any necessary vaccinations before resuming sexual activity. Since you and your partner have been vaccinated with the 9-valent HPV vaccine, this will help protect against the most common strains of HPV that cause genital warts and cervical cancer. As for the timeline, it is often recommended to wait at least three months after the last treatment or until you receive confirmation of negative HPV tests before engaging in unprotected sexual intercourse. However, this can vary based on individual circumstances, so it is best to consult your healthcare provider for personalized advice.

3. Need for Further Testing for Your Partner: Your partner has already undergone treatment for genital warts and has had a negative HPV DNA test. If there are no visible lesions and the follow-up tests remain negative, further testing may not be necessary at this time. However, it is essential for your partner to continue regular follow-ups with their healthcare provider to monitor for any recurrence of warts or changes in HPV status. If your partner experiences any new symptoms or concerns, they should seek medical advice promptly.

4. Contraception and Pregnancy Plans: If both you and your partner are comfortable and have been cleared of any active infections, you can consider resuming unprotected sexual activity, which could lead to pregnancy. However, it is essential to have open communication with your partner about your concerns and to ensure that both of you feel secure in your health status. Additionally, continuing with regular gynecological check-ups and screenings is vital for monitoring your reproductive health.

In summary, while your current testing suggests that you are likely not infected with the strains of HPV that cause genital warts, ongoing communication with your healthcare provider is essential for managing your health and relationship concerns. It is also crucial to maintain open dialogue with your partner about your feelings and any apprehensions regarding resuming sexual activity. Regular follow-ups and vaccinations will further enhance your protection against HPV.

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