Managing Menopause: Comparing Plant-Based Estrogen to Prescription Treatments

Q: Managing Menopause: Comparing Plant-Based Estrogen to Prescription Treatments

Hello, Zhenzhen： Both options are acceptable, but soy isoflavones are considered a self-paid health supplement. <br>Using Vinina for 4 to 6 years is generally acceptable, but regular follow-up with mammography and gynecological check-ups is necessary.

Estrogen therapy during menopause?

I experienced significant menopausal symptoms at the age of 53, but in the past year, hot flashes, skin itching, and palpitations have greatly affected my life, especially the hot flashes at night, which disrupt my sleep quality.
The itching also makes it difficult for me to concentrate.
When the hot flashes occur, my heart rate increases and my blood pressure rises, leading me to wonder if I might have heart disease.
By chance, I took a dietary supplement containing equol and soy isoflavones, and after a while, I noticed a significant improvement in both the hot flashes and skin itching.
However, this requires financial expenditure.
Later, I consulted a gynecologist, who listened to my symptoms and confirmed that I was in menopause.
The doctor prescribed Vivelle-Dot for me to take for a month, and if my condition improves, I could switch to a lower dose.
I would like to ask the doctor whether plant-based soy isoflavones or the medication Vivelle-Dot has more side effects and potential harm to the body, and if choosing plant-based estrogen would be more suitable.

Zhenzhen, 50~59 year old female. Ask Date: 2024/02/27

Dr. Lin Xinwang reply Obstetrics and Gynecology

Hello, Zhenzhen: Both options are acceptable, but soy isoflavones are considered a self-paid health supplement.
Using Vinina for 4 to 6 years is generally acceptable, but regular follow-up with mammography and gynecological check-ups is necessary.

Reply Date: 2024/02/27

More Info

Managing menopause can be a challenging experience, especially when symptoms like hot flashes, skin itching, and palpitations significantly impact daily life and sleep quality. It's great to hear that you've found some relief with plant-based supplements like soy isoflavones, which are known for their phytoestrogen properties. Let's delve deeper into the comparison between plant-based estrogen and prescription treatments like Vivelle-Dot (the brand name for estradiol patches).

Understanding Menopause Symptoms
Menopause typically occurs around the age of 51 and is characterized by the cessation of menstruation and a decline in estrogen levels. Common symptoms include hot flashes, night sweats, mood swings, sleep disturbances, and skin changes. The symptoms you described, such as hot flashes, skin itching, and palpitations, are indeed common during this transition. It's important to monitor these symptoms closely, as they can affect your quality of life.

Plant-Based Estrogens vs. Prescription Treatments
1. Plant-Based Estrogens (Phytoestrogens):
- Sources: Phytoestrogens are naturally occurring compounds found in plants, with soy isoflavones being one of the most studied. Other sources include flaxseeds, red clover, and certain legumes.

- Mechanism: They mimic estrogen in the body but are much weaker than the estrogen produced by the ovaries. They can bind to estrogen receptors and may help alleviate some menopausal symptoms.

- Benefits: Many women report improvements in hot flashes and other symptoms when using soy isoflavones. They are generally considered safe with fewer side effects compared to hormone replacement therapy (HRT).

- Side Effects: While generally safe, some women may experience gastrointestinal upset or allergic reactions. Long-term effects are still being studied, particularly regarding breast cancer risk.

2. Prescription Treatments (e.g., Vivelle-Dot):
- Composition: Vivelle-Dot contains estradiol, a form of estrogen that is identical to the hormone produced by the ovaries.

- Effectiveness: HRT is often more effective for severe menopausal symptoms, including hot flashes and vaginal dryness. It can also help prevent osteoporosis.

- Side Effects: Potential side effects include bloating, breast tenderness, mood changes, and an increased risk of blood clots, stroke, and certain cancers (especially with long-term use). It's crucial to discuss these risks with your healthcare provider.

Making an Informed Decision
Choosing between plant-based estrogens and prescription treatments depends on several factors, including the severity of your symptoms, personal health history, and preferences regarding natural versus synthetic treatments. Here are some considerations:
- Symptom Severity: If your symptoms are mild, plant-based options may be sufficient. However, if they are significantly affecting your quality of life, HRT might be more appropriate.

- Health History: Your personal and family medical history (e.g., history of breast cancer, cardiovascular disease) should guide your choice. Discuss these factors with your healthcare provider.

- Monitoring: If you start on Vivelle-Dot, regular follow-ups with your doctor are essential to monitor for side effects and adjust the dosage as needed.

Conclusion
In summary, both plant-based estrogens and prescription treatments have their pros and cons. Plant-based options like soy isoflavones can be a good starting point, especially if you've experienced relief from them. However, if your symptoms persist or worsen, discussing the possibility of HRT with your healthcare provider is advisable. They can help you weigh the benefits and risks based on your individual health profile and preferences. Always prioritize open communication with your healthcare provider to ensure the best management of your menopause symptoms.

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