Male Pattern Baldness: Challenges and Treatment Options - Dermatology

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The efficacy of physical and pharmacological treatments for male pattern baldness is limited?


Hello, doctor.
Some of my family members have severe male pattern baldness, including my aunt, uncle, and grandmother.
I started experiencing early-onset male pattern baldness at around 16 years old, with hair loss primarily on the crown of my head.
At that time, I took a medication with the same dosage and ingredients as Finasteride (called Farulining), but it was not effective.
Later, after using Rogaine and a hair growth cap, my hair loss situation improved significantly, and I switched my oral medication to a diuretic.
However, recently (after using the hair growth solution, hair growth cap, and diuretic for over a year), my hair loss has increased again, and the area affected has expanded (including my forehead and the sides of my forehead).
My current treatment regimen includes taking one diuretic pill daily, applying hair growth solution every day, wearing the hair growth cap every other day, and taking hair-related supplements daily.
I would like to ask the doctor if male pattern baldness is now uncontrollable, or if there are any other potential causes of hair loss.

nan guo de ren, 10~19 year old female. Ask Date: 2024/02/28

Dr. Li Yufen reply Dermatology


Hello: For a detailed introduction to male pattern baldness, you can refer to Dr.
Huang Yu-Hui's article at https://www1.cgmh.org.tw/cosmetic/contents/medi05.htm and Dr.
Hsieh Tsung-Ting's article at https://www.zlclinic.com.tw/article_d.php?lang=tw&tb=4&cid=14&id=407.
If the skin symptoms do not improve or worsen, it is advisable to consult a dermatologist nearby at https://www.derma.org.tw/finddoctor/.
Thank you!

Reply Date: 2024/02/28

More Info


Understanding male pattern baldness, also known as androgenetic alopecia, is crucial for both patients and healthcare providers. This condition is characterized by a progressive thinning of hair, typically starting at the temples and crown of the head. It is primarily influenced by genetic factors and hormonal changes, particularly the effects of dihydrotestosterone (DHT), a derivative of testosterone. Given your family history of severe hair loss, it is likely that you have a genetic predisposition to this condition.

At 16 years old, experiencing early-onset male pattern baldness can be distressing, and it is understandable that you have sought various treatment options. The medications you mentioned, such as finasteride (often marketed under the brand name Propecia), work by inhibiting the conversion of testosterone to DHT, thereby potentially slowing hair loss and promoting regrowth. However, individual responses to these treatments can vary significantly.
You noted that you initially used a medication with a similar composition to finasteride, but the results were not satisfactory. Switching to topical treatments like minoxidil (often referred to as Rogaine or 落健) can be beneficial for some individuals, as it works by increasing blood flow to hair follicles and prolonging the growth phase of hair. The use of a hair growth cap, which often utilizes low-level laser therapy, is another option that some patients find helpful, although scientific evidence supporting its efficacy is still emerging.

Despite your efforts with these treatments, it is concerning that you are experiencing increased hair loss again after a period of improvement. This could be attributed to several factors:
1. Progression of the Condition: Male pattern baldness is progressive, meaning that even with treatment, the condition can continue to advance. It is essential to have realistic expectations regarding the effectiveness of any treatment.

2. Hormonal Fluctuations: Hormonal changes, particularly during adolescence and early adulthood, can impact hair loss. Stress, diet, and overall health can also play significant roles.

3. Underlying Health Issues: Conditions such as thyroid disorders, iron deficiency anemia, or autoimmune diseases can contribute to hair loss. It may be worthwhile to consult with a healthcare provider to rule out any underlying medical conditions that could be exacerbating your hair loss.

4. Medication Side Effects: Some medications can have side effects that include hair loss. If you are taking other medications or supplements, it is essential to discuss these with your healthcare provider.

5. Inconsistent Treatment: Consistency is key with treatments like minoxidil and finasteride. If the application or dosage is not maintained as prescribed, the effectiveness may diminish.

Given your current treatment regimen, it may be beneficial to consult with a dermatologist or a specialist in hair restoration. They can provide a comprehensive evaluation of your scalp and hair health, assess your current treatment plan, and discuss additional options, such as:
- Platelet-Rich Plasma (PRP) Therapy: This involves drawing your blood, processing it to concentrate the platelets, and injecting it into the scalp to stimulate hair growth.

- Hair Transplant Surgery: For more advanced cases, hair transplant surgery may be an option, where hair follicles are moved from areas of the scalp with dense hair to balding areas.

- Alternative Medications: There are other medications and treatments available that may be effective, depending on your specific situation.

In conclusion, while male pattern baldness can be challenging to manage, especially with a family history, there are various treatment options available. It is essential to maintain open communication with your healthcare provider to explore the most effective strategies tailored to your needs. Regular follow-ups can help monitor the progression of hair loss and adjust treatments as necessary.

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