VPC Recurrence After Catheter Ablation: Key Insights - Cardiology

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Regarding the issue of recurrence after VPC (Ventricular Premature Contractions) ablation?


Hello, doctor! I have a condition known as ventricular premature contractions (VPC), with a daily occurrence that fluctuates significantly, ranging from as few as 1,000 to nearly 20,000.
About four years ago, I underwent catheter ablation.
During the procedure, I could hear the heartbeat monitoring, and after the ablation, my heart rhythm became very regular.
The electrocardiogram before my discharge also pleased the physician.
However, just three to four days after returning home, the symptoms recurred (I can feel missed beats in my pulse), and the frequency of occurrences is similar to what it was before the procedure.
I have continued taking medication (currently on rhythm control and heart-strengthening drugs).
I have since switched to a second hospital for consultation, and this physician suggested that the abnormal electrical discharge sites may have been located deeper and difficult to ablate completely, as there was a concern that aggressive ablation could damage the heart.
My question is, if I have five abnormal discharge points labeled A, B, C, D, and E, could it be that during the ablation, only three of them (for example, A, D, and E) were active, while B and C were not, leaving behind some abnormal discharge points that could lead to recurrence? Additionally, is it possible that the points that were ablated could "heal" and start discharging again? In this situation, what are the chances of a successful outcome if a second ablation is performed? Thank you for your patience in reading this, and thank you!

Ryan, 30~39 year old female. Ask Date: 2024/03/01

Dr. Huang Yinghe reply Cardiology


Hello: It is possible for the heart to have different abnormal electrical discharge points.
When only some of these discharge points are addressed during surgery, the remaining points may not be affected, which can lead to recurrence.
After ablation, it is also possible for these points to redevelop or become active again after a period of time, increasing the likelihood of recurrence.
The exact situation generally needs to be determined through a detailed electrophysiological examination by a physician.
However, if there is a reduction in the frequency of ventricular premature contractions (VPCs) after ablation, or if it improves the effectiveness of medication, it can lower the risk of cardiomyopathy or heart failure caused by frequent VPCs.
Ablation procedures carry certain risks, and whether to undergo a second procedure should be decided in close collaboration with your physician after discussing treatment options.

Reply Date: 2024/03/01

More Info


Understanding the recurrence of ventricular premature contractions (VPCs) after catheter ablation is a complex issue that involves several factors. VPCs are common arrhythmias characterized by early heartbeats originating from the ventricles. While catheter ablation is a well-established treatment for VPCs, recurrence can occur for various reasons.

Firstly, it's important to understand that during the initial ablation procedure, the electrophysiologist targets specific areas of the heart where abnormal electrical activity is believed to originate. If there are multiple sites of abnormal electrical activity (as you mentioned, points A, B, C, D, and E), it is possible that not all of these sites are successfully ablated during the first procedure. If only a subset of these sites (for example, A, D, and E) is treated, the remaining sites (B and C) can continue to generate VPCs, leading to a recurrence of symptoms.

Another factor to consider is the depth and accessibility of the abnormal electrical sites. If the abnormal focus is located deeper within the heart muscle or in a region that is difficult to reach, the physician may opt to avoid aggressive ablation techniques to prevent complications, such as perforation of the heart. This cautious approach can result in incomplete ablation, allowing for the persistence of VPCs.

Moreover, the phenomenon of "healing" or "reconnection" at the ablation site can also contribute to recurrence. After ablation, the heart tissue may undergo a healing process where scar tissue forms. In some cases, this scar tissue can become electrically active again, leading to the re-emergence of VPCs. This is particularly relevant if the ablation was not thorough or if the underlying substrate for VPCs remains unchanged.

Regarding your question about the likelihood of success with a second ablation procedure, it generally depends on several factors, including the experience of the electrophysiologist, the specific characteristics of your arrhythmia, and the overall health of your heart. Many patients do experience significant improvement after a second ablation, especially if the first procedure identified and treated some of the problematic sites. However, the success rate can vary, and some patients may require multiple procedures to achieve satisfactory control of their VPCs.

In conclusion, the recurrence of VPCs after catheter ablation can be attributed to incomplete ablation of all abnormal sites, the depth of the abnormal electrical activity, and the potential for scar tissue to become electrically active again. If you are experiencing a significant burden of VPCs, it is advisable to discuss your concerns with your electrophysiologist, who can evaluate your specific situation and determine the best course of action. This may include considering a repeat ablation, adjusting your medication regimen, or exploring other therapeutic options. Regular follow-up and monitoring are crucial in managing your condition effectively.

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