Can You Safely Extend Menstruation with Medications for 20 Days? - Obstetrics and Gynecology

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Can menstrual regulation medication be taken continuously for 20 days?


Hello, doctor.
I was originally expecting my period to start on February 27.
However, due to being away recently, I began taking Medroxyprogesterone (known as Metrone) on February 24 to delay my period.
My period has not arrived yet, and I would like to postpone it until after March 15.
However, the pharmacy advised against taking it for more than 10 days.
Can I continue taking Medroxyprogesterone until March 15? How long after stopping the medication will my period return? Thank you, doctor.

Wu, 50~59 year old female. Ask Date: 2024/03/04

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, you can try this: if your period starts, stop taking the medication.
Generally, your period will come about 4 days after stopping the medication.
Wishing you good health!

Reply Date: 2024/03/04

More Info


When it comes to extending menstruation using medications like Medroxyprogesterone (often referred to by brand names such as Provera or in your case, 美婷娜), it is crucial to understand the implications and potential risks involved. Medroxyprogesterone is a synthetic form of progesterone, a hormone that plays a key role in regulating the menstrual cycle. While it can be used to delay menstruation, there are specific guidelines and considerations to keep in mind.

Firstly, it is generally not recommended to extend the use of Medroxyprogesterone beyond the prescribed duration, which is typically around 10 days. Prolonged use can lead to various side effects and complications. These may include hormonal imbalances, breakthrough bleeding, or even more severe reactions such as blood clots, especially in individuals with pre-existing risk factors. The pharmacy's advice to limit the use to 10 days is based on these safety considerations.

If you were to take Medroxyprogesterone continuously until March 15, you would be extending the medication's use beyond the recommended period, which could increase the risk of adverse effects. Moreover, the body may respond unpredictably to extended use, and it could take longer for your menstrual cycle to normalize after stopping the medication. Typically, menstruation should resume within a few days to a couple of weeks after discontinuing the medication, but this can vary based on individual hormonal levels and overall health.

If you are considering delaying your period for personal reasons, it is essential to consult with a healthcare provider who can assess your specific situation. They can provide personalized advice, taking into account your medical history, any underlying health conditions, and the potential risks associated with extending the medication's use.
In addition, if you have any concerns about your menstrual cycle or the use of hormonal medications, it is always best to discuss these with a healthcare professional. They can help you weigh the benefits and risks and may suggest alternative methods for managing your menstrual cycle that are safer and more effective.

In summary, while Medroxyprogesterone can be used to delay menstruation, it is not advisable to extend its use beyond the recommended duration without medical supervision. Always prioritize your health and safety by consulting with a healthcare provider before making decisions regarding hormonal medications.

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