ST Segment Changes in ECG: Insights for Heart Health - Cardiology

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Interpretation of ST Segment in Electrocardiogram (ECG)


Hello Dr.
Wu, I apologize for the interruption.
I do not have hypertension, diabetes, or hyperlipidemia.
I am 172 cm tall and weigh 73 kg, and I usually have a habit of exercising.
Recently, I have been recovering from APL and have experienced some atypical symptoms of myocardial infarction.
Sometimes I feel pain in my shoulder near my neck, and at times there is aching in my left upper back.
I generally know where the pain points are, and pressing on them increases the pain (I usually take Soma for pain relief, which helps).
As for my chest, I only feel pain in the bones or muscles during rehabilitation exercises.
I have never experienced chest pain (I actually don't quite understand what "pressure pain" feels like).
I have undergone several electrocardiograms and echocardiograms, all of which showed no abnormalities.
Since it is not suitable to perform other tests at this stage, I would like to ask whether ST segment changes in a resting ECG can indicate myocardial infarction.
Is it true that ST segment elevation is likely to occur only in urgent situations of severe blockage? If multiple ECGs in the recent past have not shown ST segment changes, can we interpret that there is no significant coronary artery obstruction at that moment, but this does not necessarily mean that the degree of vascular blockage is low, correct? Thank you, Dr.
Wu.

Fred, 50~59 year old female. Ask Date: 2024/03/12

Dr. Wu Xueming reply Cardiology


To determine the presence of coronary artery disease, it is recommended to perform an exercise electrocardiogram, as a resting electrocardiogram cannot assess non-specific ST changes.

Reply Date: 2024/03/12

More Info


Understanding ST segment changes in an electrocardiogram (ECG) is crucial for assessing heart health, particularly in the context of potential coronary artery disease (CAD) and myocardial ischemia. The ST segment represents the period between ventricular depolarization and repolarization, and changes in this segment can indicate various cardiac conditions.

In your case, you mentioned experiencing atypical symptoms that could be associated with cardiac issues, such as pain in the shoulder and upper back, which you have noted intensifies with pressure. While these symptoms can be concerning, it is important to differentiate between musculoskeletal pain and cardiac-related pain. The absence of typical angina symptoms, such as chest tightness or pressure, is noteworthy, as many individuals with heart conditions may not experience classic symptoms.

You are correct in noting that ST segment changes on an ECG are often indicative of acute myocardial ischemia or infarction, particularly when there is significant coronary artery blockage. In cases of acute coronary syndrome, ST segment elevation (STE) or depression (STD) can be observed. ST elevation typically suggests a complete blockage of a coronary artery, leading to a myocardial infarction, while ST depression may indicate ischemia due to partial blockage or increased myocardial oxygen demand.

However, it is essential to understand that ST segment changes are not always present in every case of CAD. Many patients with stable angina or even those with significant coronary artery disease may have normal ECGs at rest. This is particularly true if the ischemia is not severe enough to cause noticeable changes in the ST segment during the resting state. Therefore, a normal ECG does not rule out the possibility of significant coronary artery blockage; it merely indicates that there is no acute ischemic event occurring at that moment.

In your situation, the fact that multiple ECGs have not shown ST segment changes is reassuring, but it does not completely eliminate the risk of underlying coronary artery disease. It is possible for patients to have significant stenosis without exhibiting ST segment changes on an ECG, especially if the ischemia is not provoked during the resting state. This is why stress testing, such as a treadmill test or pharmacologic stress test, can be beneficial in revealing ischemic changes that may not be apparent at rest.

Given your current health status and the ongoing recovery from APL (Acute Promyelocytic Leukemia), it is understandable that further invasive testing may not be appropriate at this time. However, it is crucial to maintain close communication with your healthcare provider regarding any changes in your symptoms. If you experience new or worsening symptoms, or if your current symptoms become more frequent or severe, it may warrant further evaluation, including potential imaging studies or stress testing.

In summary, while ST segment changes are significant indicators of myocardial ischemia, their absence does not rule out the possibility of coronary artery disease. Continuous monitoring of your symptoms, regular follow-ups with your healthcare provider, and maintaining a healthy lifestyle with exercise and proper nutrition are essential components of managing your heart health. If you have any concerns or if your symptoms change, do not hesitate to seek medical advice.

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