I would like to inquire about cardiac issues following CABG (Coronary Artery Bypass Grafting)?
Hello Dr.
Huang, my father underwent CABG surgery on February 7th last year (bypassing four vessels: LAD, D1, OM2, PDA).
Although his symptoms have improved significantly after the surgery, his LVEF, MR, and TR have not shown improvement.
His NT-ProBNP decreased from 22,460 preoperatively to 2,758 currently; however, he has started experiencing shortness of breath again this year.
I have attached the ECG and echocardiogram data from before and after the CABG surgery, as well as this year's records (please log in to your Google account first, then click the link to download) (https://drive.google.com/file/d/1gtAwwEuULC5wEg-p7NyaqhvqGO3Qp1tn/view?usp=drive_link).
I would like to ask you the following questions, and I would greatly appreciate your detailed responses:
1.
In the ECG taken the day after CABG, is there still evidence of myocardial ischemia?
2.
In the ECG from this year (March 1), is there any new evidence of myocardial ischemia (or obstruction)? Is there also a complete LBBB present?
3.
In this year's echocardiogram (March 1), the MR (favoring functional) has progressed from moderate to moderate-severe, and TR has increased from mild to moderate, with new findings of mild PR and pulmonary hypertension.
Should we prioritize addressing the MR or the LBBB?
4.
Additionally, what could be the reasons for my father's LVEF and MR not improving after CABG, and even developing a new LBBB?
mady, 40~49 year old female. Ask Date: 2024/03/19
Dr. Huang Yinghe reply Cardiology
Hello: 1.
There were no significant changes in the electrocardiogram (ECG) before and after coronary artery bypass grafting (CABG), indicating the possibility of myocardial ischemia.
2.
The ECG from March 1 of this year compared to the postoperative ECG shows a new (complete) left bundle branch block (LBBB).
3.
The ejection fraction (EF) and mitral regurgitation (MR) did not improve after CABG, which may be related to the degree of pre-existing myocardial ischemia.
It is possible that a significant portion of the myocardium had already undergone necrosis prior to surgery, resulting in an inability to restore function even after blood flow is re-established.
Poor left ventricular systolic function (LVEF) over time may lead to the development of LBBB on the ECG and could also affect right heart circulation, causing tricuspid regurgitation (TR) and pulmonary hypertension.
New myocardial ischemia could also cause LBBB; however, the likelihood of vascular reocclusion within one year after CABG is low.
Postoperative medication adherence is crucial, as controlling blood pressure, using antiplatelet agents, and heart failure medications are key strategies to maintain or even improve cardiac function.
If symptoms of dyspnea do not improve with medication, it may be necessary to perform cardiac catheterization to assess the condition of the coronary vessels or consider surgical valve repair.
This should be discussed further with your father's attending physician.
Reply Date: 2024/03/19
More Info
Post-Coronary Artery Bypass Grafting (CABG) complications can be complex and multifactorial. In your father's case, despite symptomatic improvement following the surgery, persistent issues with Left Ventricular Ejection Fraction (LVEF), Mitral Regurgitation (MR), and Tricuspid Regurgitation (TR) raise important clinical questions. Let's address your queries systematically.
1. Presence of Myocardial Ischemia Post-CABG: The electrocardiogram (ECG) taken the day after CABG may still show signs of myocardial ischemia. This can occur due to several reasons, including incomplete revascularization, residual coronary artery disease, or even new ischemic events. The heart muscle may still be recovering from the stress of surgery, and transient ischemic changes can be observed. It is crucial to correlate these findings with clinical symptoms and possibly conduct further imaging studies, such as a stress test or myocardial perfusion scan, to assess for ongoing ischemia.
2. New Symptoms and ECG Findings: The development of shortness of breath (dyspnea) in March, coupled with the ECG findings, should be evaluated carefully. If the ECG shows new signs of ischemia or a complete Left Bundle Branch Block (LBBB), it could indicate new or worsening coronary artery disease or other cardiac issues. LBBB can complicate the interpretation of ischemic changes on an ECG, as it can mask or mimic ischemic patterns. Therefore, a thorough assessment, including echocardiography and possibly a cardiac catheterization, may be warranted to determine the underlying cause of these new symptoms.
3. Management of MR vs. LBBB: The echocardiogram indicating worsening MR from moderate to moderate-severe and TR from mild to moderate, along with the emergence of pulmonary hypertension, suggests that the heart is under increased stress. The decision to address MR or LBBB first depends on the clinical context. If the MR is significantly contributing to heart failure symptoms or pulmonary hypertension, it may need to be prioritized. Conversely, if LBBB is causing significant conduction issues or is associated with new ischemic symptoms, it may require attention. A multidisciplinary approach involving a cardiologist and possibly a cardiac surgeon is essential to determine the best course of action.
4. Reasons for Persistent LVEF and MR Issues Post-CABG: The lack of improvement in LVEF and the worsening MR post-CABG can be attributed to several factors. First, the underlying myocardial condition prior to surgery may have led to irreversible damage, affecting the heart's ability to contract effectively. Additionally, functional MR can arise from left ventricular dilation or dysfunction, which may not have been fully addressed during surgery. The presence of new LBBB could also indicate underlying ischemia or structural heart changes that were not corrected. Furthermore, factors such as patient age, comorbidities (like diabetes or hypertension), and overall cardiac health play significant roles in recovery and outcomes post-surgery.
In conclusion, your father's case highlights the importance of ongoing monitoring and management after CABG. It is crucial to maintain open communication with his healthcare team, who can provide tailored recommendations based on his specific clinical situation. Further diagnostic evaluations, including imaging and possibly invasive procedures, may be necessary to clarify the current state of his heart and guide appropriate treatment strategies.
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