HPV Testing and Genital Warts: What You Need to Know - Urology

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Cauliflower and HPV testing?


Last week, my partner discovered a lump under my vagina after sexual intercourse.
Initially, I didn't pay much attention to it, but later on Saturday and Sunday, I noticed cauliflower-like warts in the perineal area.
On Monday, I went to see a gynecologist, who immediately told me that it was genital warts.
I also had a Pap smear and HPV test done, and I received the reports over the past two days, both of which were normal.
However, I asked why I have genital warts but no HPV virus detected.
The testing methods were both performed using samples obtained from the cervix; the Pap smear was done using a computer, but I'm not clear on the HPV testing process.

Xi, 20~29 year old female. Ask Date: 2024/03/22

Dr. Du Shixi reply Urology


Hello: HPV testing can only indicate the presence of the virus in the area where the Pap smear is taken; generally, other areas that are not sampled cannot be confirmed.
Wishing you good health.

Reply Date: 2024/03/22

More Info


Understanding HPV Testing and Genital Warts: What You Need to Know
Human Papillomavirus (HPV) is a common sexually transmitted infection that can lead to various health issues, including genital warts and cervical cancer. It is important to understand the relationship between HPV, genital warts, and the testing methods used to diagnose these conditions.

Firstly, it is crucial to note that there are many types of HPV, and not all of them are associated with genital warts or cancer. The types that typically cause genital warts are HPV 6 and 11, which are considered low-risk types. On the other hand, high-risk types, such as HPV 16 and 18, are more commonly associated with cervical cancer. This distinction is essential when interpreting test results.

In your case, you mentioned that you discovered warts in the genital area, which were identified as condylomata acuminata (genital warts) by your gynecologist. However, your HPV test results came back negative for the virus. This situation can occur because the HPV test typically screens for high-risk types of HPV that are linked to cervical cancer, rather than the low-risk types that cause genital warts. Therefore, it is possible to have genital warts caused by HPV 6 or 11 while testing negative for high-risk HPV types.

Regarding the testing methods, the Pap smear (or Pap test) is a screening tool used primarily to detect precancerous changes in cervical cells and to identify the presence of high-risk HPV types. The HPV test can be performed simultaneously with the Pap smear, but it focuses on detecting high-risk HPV strains. If your Pap smear results were normal, it indicates that there were no abnormal cervical cells detected at the time of the test.

If you have genital warts, treatment options are available, including topical medications, cryotherapy (freezing the warts), or surgical removal. It is essential to consult with your healthcare provider to determine the best course of action based on your specific situation.

In terms of vaccination, the HPV vaccine can help prevent future infections with the most common high-risk and low-risk HPV types. If you have not been vaccinated yet, it is advisable to discuss this with your healthcare provider, as vaccination can provide additional protection against HPV-related diseases, including genital warts and cervical cancer.

Lastly, it is important to maintain regular follow-up appointments with your gynecologist, especially if you have a history of HPV or genital warts. Regular Pap smears and HPV testing can help monitor your cervical health and detect any changes early on.

In summary, while you may have genital warts, it is possible to test negative for high-risk HPV types. Understanding the differences between HPV types and the testing methods used is crucial for managing your health. If you have any concerns or questions about your diagnosis or treatment options, do not hesitate to reach out to your healthcare provider for personalized advice and guidance.

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