Colorectal issues
Hello Doctor, my mother (63) underwent a colonoscopy at the end of January and a 3 to 4 cm ulcer was found in the rectal area.
The doctor mentioned that another examination would be done in March to see if there was any improvement.
After the March examination, it was found that the ulcer remained the same, and a stool softener was prescribed, with a follow-up scheduled for June.
Could you please clarify if there are no medical treatments for rectal ulcers? Are rectal ulcers common? Is there a risk of cancer development? Are rectal ulcers the same as ulcerative colitis? I appreciate your assistance in addressing these concerns.
Attached is the biopsy report for your reference.
I am quite worried about my mother's health.
Thank you.
Pathologic diagnosis: Rectum, endoscopic biopsy --- Ulcer with mucosal hyperplasia, chronic active inflammation, and focal glandular atypia.
See Comment.
Ancillary study for diagnosis: 1.
PAS and acid-fast stains done.
No fungal elements or acid-fast mycobacteria found.
2.
Recut and IHC stains for CMV (-), AE1/AE3 (highlight epithelial cells), and p53 (mildly increased expression) done.
Gross description: The specimen consists of 4 pieces of tan soft tissue, up to 0.2x0.1x0.1 cm.
All for section.
Microscopic description: Section shows rectal mucosa with ulcer, mucosal hyperplasia, acute inflammation, and focal glandular atypia.
Comment: Mucosal prolapse polyp with ulceration can be considered.
The focal glandular atypia may be ulcer-related.
However, the specimen is limited and may be non-representative for the entire lesion.
If invasive adenocarcinoma is highly suspected clinically, rebiopsy is suggested.
Niming, 60~69 year old female. Ask Date: 2024/03/24
Dr. Chen Shidian reply Gastroenterology and Hepatology
Benign anal ulcers are common in the elderly and can be managed with treatment and follow-up.
Reply Date: 2024/03/24
More Info
Understanding rectal ulcers is crucial for both patients and their families, especially when faced with the uncertainty of diagnosis and treatment options. Your mother's case, involving a 3 to 4 cm ulcer in the rectal area, raises several important questions regarding the nature of the ulcer, potential treatments, and the risks associated with it.
Causes of Rectal Ulcers
Rectal ulcers can arise from various causes, including:
1. Inflammatory Bowel Disease (IBD): Conditions like ulcerative colitis and Crohn's disease can lead to ulcer formation in the rectum.
2. Infections: Certain infections, including sexually transmitted infections or bacterial infections, can cause ulcers.
3. Ischemia: Reduced blood flow to the rectal area can lead to ulceration.
4. Trauma: Physical injury or irritation from bowel movements can result in ulcers.
5. Malignancy: In some cases, rectal ulcers can be a sign of cancer, particularly if they are persistent and associated with other symptoms.
Risks and Cancer Potential
The pathology report indicates "chronic active inflammation and focal glandular atypia," which suggests that there is ongoing inflammation and some atypical cell changes. While not all rectal ulcers are cancerous, the presence of atypical cells raises concerns. It is essential to monitor these changes closely, as some ulcers can progress to cancer if left untreated. The recommendation for a follow-up biopsy is prudent, especially if there is a clinical suspicion of invasive adenocarcinoma.
Treatment Options
Regarding treatment, rectal ulcers may not always require medication, especially if they are not associated with significant symptoms. However, treatment options can include:
1. Medications: If the ulcer is due to inflammatory bowel disease, medications such as corticosteroids or immunosuppressants may be prescribed to reduce inflammation. Antibiotics may be necessary if an infection is present.
2. Dietary Changes: A diet high in fiber can help ease bowel movements and reduce irritation in the rectal area.
3. Sitz Baths: Warm baths can provide relief and promote healing.
4. Surgical Intervention: In cases where the ulcer does not heal or if there is a significant risk of cancer, surgical options may be considered.
Monitoring and Follow-Up
The follow-up colonoscopy scheduled for June is crucial. It will allow the physician to assess whether the ulcer is healing or if there are any changes that warrant further investigation. Regular monitoring is essential, especially given the potential for malignancy.
Distinction from Ulcerative Colitis
It is important to differentiate between rectal ulcers and ulcerative colitis. While both conditions can cause ulcers in the rectal area, ulcerative colitis is a chronic inflammatory condition that affects the colon and rectum, leading to symptoms such as diarrhea, abdominal pain, and rectal bleeding. Rectal ulcers can occur independently and may not necessarily indicate ulcerative colitis.
Conclusion
In summary, rectal ulcers can arise from various causes, and while they may not always indicate a severe condition, the presence of atypical cells in the biopsy requires careful monitoring. Treatment may vary based on the underlying cause, and regular follow-ups are essential to ensure that any changes are promptly addressed. It is advisable to maintain open communication with your mother's healthcare provider to discuss any concerns and to ensure that she receives appropriate care tailored to her specific situation.
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